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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A8MVV6 TSPAN4 Tetraspanin Homo sapiens (Human) 174 aa

Protein Details: A8MVV6 (TSPAN4)

Protein Information
AccessionA8MVV6
Protein NamesTetraspanin
Gene SymbolTSPAN4
OrganismHomo sapiens (Human)
Length174 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAIGFVGCLG11AIKENKCLLL21TFFLLLLLVF31LLEATIAILF41FAYTDKIDRY
51-10051AQQDLKKGLH61LYGTQGNVGL71TNAWSIIQTD81FRCCGVSNYT91DWFEVYNATR
101-150101VPDSCCLEFS111ESCGLHAPGT121WWKAPCYETV131KVWLQENLLA141VGIFGLCTAL
151-174151VQILGLTFAM161TMYCQVVKAD171TYCA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
8 Tetraspanin/Peripherin - -
GPS-Palm: 0.97
Deep-Palm: 0.19
17 Tetraspanin/Peripherin - -
GPS-Palm: 0.68
Deep-Palm: 0.98
83 - - -
GPS-Palm: 0.76
Deep-Palm: 0.65
84 - - -
GPS-Palm: 0.82
Deep-Palm: 0.64
105 - - -
Deep-Palm: 0.36
106 - - -
Deep-Palm: 0.26
113 - - -
Deep-Palm: 0.13
126 - - -
Deep-Palm: 0.91
147 - - -
GPS-Palm: 0.81
Deep-Palm: 0.83
164 SWISSPALM DBPTM CYSMODDB -
HeLa (29575903)
-
GPS-Palm: 0.66
Deep-Palm: 0.02
173 - - -
GPS-Palm: 0.95
Deep-Palm: 0.01
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
46 S → C 0.003460 SNP Missense Mutation CESC
228 C → Y 0.002288 SNP Missense Mutation STAD
81* C → ? 0.005618 SNP Nonsense Mutation PAAD