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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
A8MW50 LDHB L-lactate dehydrogenase (EC 1.1.1.27) Homo sapiens (Human) 232 aa

Protein Details: A8MW50 (LDHB)

Protein Information
Accession A8MW50
Protein Names L-lactate dehydrogenase (EC 1.1.1.27)
Gene Symbol LDHB
Organism Homo sapiens (Human)
Length 232 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.750
24/46 (52.2%)
4
PC3 cells
Specificity: 0.125
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.125
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MATLKEKLIA11PVAEEEATVP21NNKITVVGVG31QVGMACAISI41LGKSLADELA
51-10051LVDVLEDKLK61GEMMDLQHGS71LFLQTPKIVA81DKDYSVTANS91KIVVVTAGVR
101-150101QQEGESRLNL111VQRNVNVFKF121IIPQIVKYSP131DCIIIVVSNP141VDILTYVTWK
151-200151LSGLPKHRVI161GSGCNLDSAR171FRYLMAEKLG181IHPSSCHGWI191LGEHGDSSVA
201-232201VWSGVNVAGV211SLQELNPEMG221TDNDSENWKE231VH
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
36 Prediction (Medium) - -
164 CYSMODDB SWISSPALM DBPTM Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
100 R → C 0.002506 SNP Missense Mutation COAD
158 R → C 0.001887 SNP Missense Mutation UCEC
204 G → C 0.002506 SNP Missense Mutation COAD
? ? → ? 0.002506 SNP Nonstop Mutation COAD