Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| A8MX94 | GSTP1 | Glutathione S-transferase P (EC 2.5.1.18) … | Homo sapiens (Human) | 174 aa |
Protein Details: A8MX94 (GSTP1)
Protein Information
| Accession | A8MX94 |
|---|---|
| Protein Names | Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi) |
| Gene Symbol | GSTP1 |
| Organism | Homo sapiens (Human) |
| Length | 174 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 29575903 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPPYTVVYFP11VRGRCAALRM21LLADQGQSWK31EEVVTVETWQ41EGSLKASCLY
51-10051GQLPKFQDGD61LTLYQSNTIL71RHLGRTLGLY81GKDQQEAALV91DMVNDGVEDL
101-150101RCKYISLIYT111NYISFADYNL121LDLLLIHEVL131APGCLDAFPL141LSAYVGRLSA
151-174151RPKLKAFLAS161PEYVNLPING171NGKQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 15 | Glutathione S-transferase, N-terminal Thioredoxin-like superfamily Glutaredoxin | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.93
|
|
| 48 | SWISSPALM DBPTM CYSMODDB | Glutathione S-transferase, N-terminal Thioredoxin-like superfamily Glutaredoxin | - |
Unknown
(32651440)
cerebral cortex
(36430497)
|
GPS-Palm: 0.84
Deep-Palm: 0.98
|
| 102 | - | - | - |
Deep-Palm: 0.43
|
|
| 134 | - | - | - |
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
cerebral cortex
Specificity: 0.308
4/4 (100.0%)
3
PC3
Specificity: 0.231
3/3 (100.0%)
1
HeLa cell
Specificity: 0.077
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.077
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.308
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 71 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 183 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |