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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
B0QY89 EIF3L; EIF3EIP; EIF3S6IP Eukaryotic translation initiation factor 3 … Homo sapiens (Human) 607 aa

Protein Details: B0QY89 (EIF3L)

Protein Information
Accession B0QY89
Protein Names Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein)
Gene Symbol EIF3L; EIF3EIP; EIF3S6IP
Organism Homo sapiens (Human)
Length 607 aa
Isoforms No isoforms
Related PMIDs 31382980 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
U937 cells
Specificity: 0.500
1/1 (100.0%)
1
PC3 cells
Specificity: 0.500
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MARGLGKASG11FPAGPSGAEL21PASGRRRGPL31ISLFPAVLAS41EAAMSYPADD
51-10051YESEAAYDPY61AYPSDYDMHT71GDPKQDLAYE81RQYEQQTYQV91IPEVIKNFIQ
101-150101YFHKTVSDLI111DQKVYELQAS121RVSSDVIDQK131VYEIQDIYEN141SWTKLTERFF
151-200151KNTPWPEAEA161IAPQVGNDAV171FLILYKELYY181RHIYAKVSGG191PSLEQRFESY
201-250201YNYCNLFNYI211LNADGPAPLE221LPNQWLWDII231DEFIYQFQSF241SQYRCKTAKK
251-300251SEEEIDFLRS261NPKIWNVHSV271LNVLHSLVDK281SNINRQLEVY291TSGGDPESVA
301-350301GEYGRHSLYK311MLGYFSLVGL321LRLHSLLGDY331YQAIKVLENI341ELNKKSMYSR
351-400351VPECQVTTYY361YVGFAYLMMR371RYQDAIRVFA381NILLYIQRTK391SMFQRTTYKY
401-450401EMINKQNEQM411HALLAIALTM421YPMRIDESIH431LQLREKYGDK441MLRMQKGDPQ
451-500451VYEELFSYSC461PKFLSPVVPN471YDNVHPNYHK481EPFLQQLKVF491SDEVQQQAQL
501-550501STIRSFLKLY511TTMPVAKLAG521FLDLTEQEFR531IQLLVFKHKM541KNLVWTSGIS
551-600551ALDGEFQSAS561EVDFYIDKDM571IHIADTKVAR581RYGDFFIRQI591HKFEELNRTL
601-607601KKMGQRP
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
354 Prediction (Low) - -
460 CYSMODDB SWISSPALM DBPTM RNA polymerase I-associated factor PAF67 -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
216 R → C 0.001014 SNP Missense Mutation BRCA
216 R → C 0.002141 SNP Missense Mutation SKCM
217 S → C 0.002294 SNP Missense Mutation OV
279 R → C 0.001969 SNP Missense Mutation HNSC
400 R → C 0.010870 SNP Missense Mutation ACC
467 Y → C 0.003460 SNP Missense Mutation CESC