Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B0QY90 | EIF3L; EIF3EIP; EIF3S6IP; hCG_41840 | Eukaryotic translation initiation factor 3 … | Homo sapiens (Human) | 466 aa |
Protein Details: B0QY90 (EIF3L)
Protein Information
| Accession | B0QY90 |
|---|---|
| Protein Names | Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein) |
| Gene Symbol | EIF3L; EIF3EIP; EIF3S6IP; hCG_41840 |
| Organism | Homo sapiens (Human) |
| Length | 466 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 29575903 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.833
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
5
Jurkat T cells
Specificity: 0.833
5/25 (20.0%)
1
PC3 cells
Specificity: 0.167
1/4 (25.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSYRPVVSPV11MSLTRRCMRS21RTSMRTDAVF31LILYKELYYR41HIYAKVSGGP
51-10051SLEQRFESYY61NYCNLFNYIL71NADGPAPLEL81PNQWLWDIID91EFIYQFQSFS
101-150101QYRCKTAKKS111EEEIDFLRSN121PKIWNVHSVL131NVLHSLVDKS141NINRQLEVYT
151-200151SGGDPESVAG161EYGRHSLYKM171LGYFSLVGLL181RLHSLLGDYY191QAIKVLENIE
201-250201LNKKSMYSRV211PECQVTTYYY221VGFAYLMMRR231YQDAIRVFAN241ILLYIQRTKS
251-300251MFQRTTYKYE261MINKQNEQMH271ALLAIALTMY281PMRIDESIHL291QLREKYGDKM
301-350301LRMQKGDPQV311YEELFSYSCP321KFLSPVVPNY331DNVHPNYHKE341PFLQQLKVFS
351-400351DEVQQQAQLS361TIRSFLKLYT371TMPVAKLAGF381LDLTEQEFRI391QLLVFKHKMK
401-450401NLVWTSGISA411LDGEFQSASE421VDFYIDKDMI431HIADTKVARR441YGDFFIRQIH
451-466451KFEELNRTLK461KMGQRP
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 17 | Prediction (Medium) | - | - |
| 213 | Prediction (Low) | - | - |
| 319 | Experimental CYSMODDB SWISSPALM DBPTM | RNA polymerase I-associated factor PAF67 | 29575903 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 216 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 216 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 217 | S → C | 0.002294 | SNP | Missense Mutation | OV |
| 279 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 400 | R → C | 0.010870 | SNP | Missense Mutation | ACC |
| 467 | Y → C | 0.003460 | SNP | Missense Mutation | CESC |