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UniProt ID	Gene Symbol	Protein Name	Organism	Length	Action
B0QY90	EIF3L	Eukaryotic translation initiation factor 3 …	Homo sapiens (Human)	466 aa

Protein Details: B0QY90 (EIF3L)

Protein Information

Accession	B0QY90
Protein Names	Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein)
Gene Symbol	EIF3L
Organism	Homo sapiens (Human)
Length	466 aa
Isoforms	No isoforms
Related PMIDs	No related PMIDs
Database Sources	CysModDB dbPTM SwissPalm

These studies detected palmitoylation of this protein in the samples.

Protein Sequence

Types:
Experimental Database High Prediction Non-palmitylated Cys

1-501MSYRPVVSPV11MSLTRRCMRS21RTSMRTDAVF31LILYKELYYR41HIYAKVSGGP

51-10051SLEQRFESYY61NYCNLFNYIL71NADGPAPLEL81PNQWLWDIID91EFIYQFQSFS

101-150101QYRCKTAKKS111EEEIDFLRSN121PKIWNVHSVL131NVLHSLVDKS141NINRQLEVYT

151-200151SGGDPESVAG161EYGRHSLYKM171LGYFSLVGLL181RLHSLLGDYY191QAIKVLENIE

201-250201LNKKSMYSRV211PECQVTTYYY221VGFAYLMMRR231YQDAIRVFAN241ILLYIQRTKS

251-300251MFQRTTYKYE261MINKQNEQMH271ALLAIALTMY281PMRIDESIHL291QLREKYGDKM

301-350301LRMQKGDPQV311YEELFSYSCP321KFLSPVVPNY331DNVHPNYHKE341PFLQQLKVFS

351-400351DEVQQQAQLS361TIRSFLKLYT371TMPVAKLAGF381LDLTEQEFRI391QLLVFKHKMK

401-450401NLVWTSGISA411LDGEFQSASE421VDFYIDKDMI431HIADTKVARR441YGDFFIRQIH

451-466451KFEELNRTLK461KMGQRP

Palmitoylation Sites Details

Position	Database	Domains	Literature (PMID/Cell-Tissue)	Mass(PMID/Cell-Tissue)	Prediction Scores
17		-	-	-	GPS-Palm: 0.85 Deep-Palm: 0.85
63		-	-	-	Deep-Palm: 0.30
104		-	-	-	Deep-Palm: 0.49
213		-	-	-	GPS-Palm: 0.69 Deep-Palm: 0.10
319	SWISSPALM DBPTM CYSMODDB	RNA polymerase I-associated factor PAF67	HeLa (29575903)	-	Deep-Palm: 0.26

Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)

Conservation score for cysteine

PhyloP for Cysteine

PhastCons Conservation Scores for Cysteine

TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position	Amino Acid Change	Frequency	Type	Function	Cancer Type
216	R → C	0.001014	SNP	Missense Mutation	BRCA
216	R → C	0.002141	SNP	Missense Mutation	SKCM
217	S → C	0.002294	SNP	Missense Mutation	OV
279	R → C	0.001969	SNP	Missense Mutation	HNSC
400	R → C	0.010870	SNP	Missense Mutation	ACC
467	Y → C	0.003460	SNP	Missense Mutation	CESC