Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B0YJC4 | VIM | Vimentin | Homo sapiens (Human) | 431 aa |
Protein Details: B0YJC4 (VIM)
Protein Information
| Accession | B0YJC4 |
|---|---|
| Protein Names | Vimentin |
| Gene Symbol | VIM |
| Organism | Homo sapiens (Human) |
| Length | 431 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 31382980 32944167 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSTRSVSSSS11YRRMFGGPGT21ASRPSSSRSY31VTTSTRTYSL41GSALRPSTSR
51-10051SLYASSPGGV61YATRSSAVRL71RSSVPGVRLL81QDSVDFSLAD91AINTEFKNTR
101-150101TNEKVELQEL111NDRFANYIDK121VRFLEQQNKI131LLAELEQLKG141QGKSRLGDLY
151-200151EEEMRELRRQ161VDQLTNDKAR171VEVERDNLAE181DIMRLREKLQ191EEMLQREEAE
201-250201NTLQSFRQDV211DNASLARLDL221ERKVESLQEE231IAFLKKLHEE241EIQELQAQIQ
251-300251EQHVQIDVDV261SKPDLTAALR271DVRQQYESVA281AKNLQEAEEW291YKSKFADLSE
301-350301AANRNNDALR311QAKQESTEYR321RQVQSLTCEV331DALKGTNESL341ERQMREMEEN
351-400351FAVEAANYQD361TIGRLQDEIQ371NMKEEMARHL381REYQDLLNVK391MALDIEIATY
401-431401RKLLEGEESR411ISLPLPNFSS421LNLRGKHFIS431L
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 328 | SWISSPALM DBPTM CYSMODDB | Intermediate filament protein |
HeLa
(29575903)
|
Unknown
(32651440)
|
GPS-Palm: 0.65
Deep-Palm: 0.93
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
3
PC3
Specificity: 0.300
3/3 (100.0%)
2
Jurkat T cell
Specificity: 0.200
2/2 (100.0%)
1
U937 cell
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 217 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 310 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 319 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |