Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B1AH77 | RAC2 | Rac family small GTPase 2 | Homo sapiens (Human) | 148 aa |
Protein Details: B1AH77 (RAC2)
Protein Information
| Accession | B1AH77 |
|---|---|
| Protein Names | Rac family small GTPase 2 |
| Gene Symbol | RAC2 |
| Organism | Homo sapiens (Human) |
| Length | 148 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31382980 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVDSKPVNLG11LWDTAGQEDY21DRLRPLSYPQ31TDVFLICFSL41VSPASYENVR
51-10051AKWFPEVRHH61CPSTPIILVG71TKLDLRDDKD81TIEKLKEKKL91APITYPQGLA
101-148101LAKEIDSVKY111LECSALTQRG121LKTVFDEAIR131AVLCPQPTRQ141QKRACSLL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 37 | P-loop containing nucleoside triphosphate hydrolase small GTPase Rho family profile. Small GTPase Small GTPase Rho | - | - |
Deep-Palm: 0.95
|
|
| 61 | - | - | - |
Deep-Palm: 0.97
|
|
| 113 | SWISSPALM DBPTM CYSMODDB | - | - |
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.91
Deep-Palm: 0.98
|
| 134 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.96
|
|
| 145 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
PC3
Specificity: 0.800
4/4 (100.0%)
1
U937 cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 18 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 89 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 189 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |