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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
B1AKY9 ATP1A2 Sodium/potassium-transporting ATPase subunit alpha Homo sapiens (Human) 1009 aa

Protein Details: B1AKY9 (ATP1A2)

Protein Information
Accession B1AKY9
Protein Names Sodium/potassium-transporting ATPase subunit alpha
Gene Symbol ATP1A2
Organism Homo sapiens (Human)
Length 1009 aa
Isoforms No isoforms
Related PMIDs 21076176 26876311 29575903 31251020 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.818
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.818
36/46 (78.3%)
4
Cerebral cortex
Specificity: 0.091
4/4 (100.0%)
2
Jurkat T cells
Specificity: 0.045
2/25 (8.0%)
1
HeLa cells
Specificity: 0.023
1/1 (100.0%)
1
Prefrontal cortex
Specificity: 0.023
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGRGAGREYS11PAATTAENGG21GKKKQKEKEL31DELKKEVAMD41DHKLSLDELG
51-10051RKYQVDLSKG61LTNQRAQDVL71ARDGPNALTP81PPTTPEWVKF91CRQLFGGFSI
101-150101LLWIGAILCF111LAYGIQAAME121DEPSNDNLYL131GVVLAAVVIV141TGCFSYYQEA
151-200151KSSKIMDSFK161NMVPQQALVI171REGEKMQINA181EEVVVGDLVE191VKGGDRVPAD
201-250201LRIISSHGCK211VDNSSLTGES221EPQTRSPEFT231HENPLETRNI241CFFSTNCVEG
251-300251TARGIVIATG261DRTVMGRIAT271LASGLEVGRT281PIAMEIEHFI291QLITGVAVFL
301-350301GVSFFVLSLI311LGYSWLEAVI321FLIGIIVANV331PEGLLATVTV341CLTLTAKRMA
351-400351RKNCLVKNLE361AVETLGSTST371ICSDKTGTLT381QNRMTVAHMW391FDNQIHEADT
401-450401TEDQSGATFD411KRSPTWTALS421RIAGLCNRAV431FKAGQENISV441SKRDTAGDAS
451-500451ESALLKCIEL461SCGSVRKMRD471RNPKVAEIPF481NSTNKYQLSI491HEREDSPQSH
501-550501VLVMKGAPER511ILDRCSTILV521QGKEIPLDKE531MQDAFQNAYM541ELGGLGERVL
551-600551GFCQLNLPSG561KFPRGFKFDT571DELNFPTEKL581CFVGLMSMID591PPRAAVPDAV
601-650601GKCRSAGIKV611IMVTGDHPIT621AKAIAKGVGI631ISEGNETVED641IAARLNIPMS
651-700651QVNPREAKAC661VVHGSDLKDM671TSEQLDEILK681NHTEIVFART691SPQQKLIIVE
701-750701GCQRQGAIVA711VTGDGVNDSP721ALKKADIGIA731MGISGSDVSK741QAADMILLDD
751-800751NFASIVTGVE761EGRLIFDNLK771KSIAYTLTSN781IPEITPFLLF791IIANIPLPLG
801-850801TVTILCIDLG811TDMVPAISLA821YEAAESDIMK831RQPRNSQTDK841LVNERLISMA
851-900851YGQIGMIQAL861GGFFTYFVIL871AENGFLPSRL881LGIRLDWDDR891TMNDLEDSYG
901-950901QEWTYEQRKV911VEFTCHTAFF921ASIVVVQWAD931LIICKTRRNS941VFQQGMKNKI
951-1000951LIFGLLEETA961LAAFLSYCPG971MGVALRMYPL981NLLIFIYDEV991RKLILRRYPG
1001-10091001GWVEKETYY
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
91 Prediction (Low) - -
143 Prediction (Medium) - -
209 Prediction (Low) - -
341 Prediction (Medium) - -
354 Prediction (High) - -
372 Prediction (Low) - -
426 Prediction (Medium) - -
457 Prediction (Low) - -
462 Prediction (High) - -
515 Prediction (Medium) - -
553 Prediction (Medium) - -
603 Prediction (Medium) - -
660 Prediction (Medium) - -
702 CYSMODDB SWISSPALM DBPTM Prediction (High) - -
934 Prediction (High) - -
968 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
51 R → C 0.002288 SNP Missense Mutation STAD
143 C → G 0.002506 SNP Missense Mutation COAD
247 C → C 0.002033 SNP Silent LUSC
267 R → C 0.002288 SNP Missense Mutation STAD
267 R → C 0.001969 SNP Missense Mutation HNSC
428 R → C 0.002506 SNP Missense Mutation COAD
486 Y → C 0.001887 SNP Missense Mutation UCEC
510 R → C 0.001969 SNP Missense Mutation HNSC
548 R → C 0.002976 SNP Missense Mutation KIRC
664 G → C 0.001764 SNP Missense Mutation LUAD
861 G → C 0.001764 SNP Missense Mutation LUAD
861 G → C 0.001887 SNP Missense Mutation UCEC
976 R → C 0.001969 SNP Missense Mutation HNSC