Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B1AM21 | GNAQ | G protein subunit alpha q | Homo sapiens (Human) | 170 aa |
Protein Details: B1AM21 (GNAQ)
Protein Information
| Accession | B1AM21 |
|---|---|
| Protein Names | G protein subunit alpha q |
| Gene Symbol | GNAQ |
| Organism | Homo sapiens (Human) |
| Length | 170 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGERWADSQL11DSRSTHGTGE21SGKSTFIKQM31RIIHGSGYSD41EDKRGFTKLV
51-10051YQNIFTAMQA61MIRAMDTLKI71PYKYEHNKAH81AQLVREVDVE91KVSAFENPYV
101-150101DAIKSLWNDP111GIQECYDRRR121EYQLSDSTKY131YLNDLDRVAD141PAYLPTQQDV
151-170151LRVRVPTTGI161IEYPFDLQSV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 115 | SWISSPALM DBPTM CYSMODDB | G-protein alpha subunit |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.80
Deep-Palm: 0.66
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.800
4/4 (100.0%)
1
HeLa cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 10 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 356 | Y → C | 0.002141 | SNP | Missense Mutation | SKCM |