Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B1APP6 | PFKP | 6-phosphofructokinase type C (Phosphofructo-1-kinase isozyme … | Homo sapiens (Human) | 568 aa |
Protein Details: B1APP6 (PFKP)
Protein Information
| Accession | B1APP6 |
|---|---|
| Protein Names | 6-phosphofructokinase type C (Phosphofructo-1-kinase isozyme C) |
| Gene Symbol | PFKP |
| Organism | Homo sapiens (Human) |
| Length | 568 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 0.600
3/4 (75.0%)
2
Jurkat T cells
Specificity: 0.400
2/25 (8.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGRHCGYLAL11VSALACGADW21VFLPESPPEE31GWEEQMCVKL41SENRARKKRL
51-10051NIIIVAEGAI61DTQNKPITSE71KIKELVVTQL81GYDTRVTILG91HVQRGGTPSA
101-150101FDRILASRMG111VEAVIALLEA121TPDTPACVVS131LNGNHAVRLP141LMECVQMTQD
151-200151VQKAMDERRF161QDAVRLRGRS171FAGNLNTYKR181LAIKLPDDQI191PKTNCNVAVI
201-250201NVGAPAAGMN211AAVRSAVRVG221IADGHRMLAI231YDGFDGFAKG241QIKEIGWTDV
251-300251GGWTGQGGSI261LGTKRVLPGK271YLEEIATQMR281THSINALLII291GGFEAYLGLL
301-350301ELSAAREKHE311EFCVPMVMVP321ATVSNNVPGS331DFSIGADTAL341NTITDTCDRI
351-400351KQSASGTKRR361VFIIETMGGY371CGYLANMGGL381AAGADAAYIF391EEPFDIRDLQ
401-450401SNVEHLTEKM411KTTIQRGLVL421RNESCSENYT431TDFIYQLYSE441EGKGVFDCRK
451-500451NVLGHMQQGG461APSPFDRNFG471TKISARAMEW481ITAKLKEARG491RGKKFTTDDS
501-550501ICVLGISKRN511VIFQPVAELK521KQTDFEHRIP531KEQWWLKLRP541LMKILAKYKA
551-568551SYDVSDSGQL561EHVQPWSV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 5 | Prediction (High) | - | - |
| 144 | Prediction (Medium) | - | - |
| 347 | Prediction (Medium) | - | - |
| 371 | Prediction (Low) | - | - |
| 425 | Prediction (Low) | - | - |
| 502 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 44 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 44 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 48 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 48 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 48 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 117 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 118 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 343 | C → C | 0.004577 | SNP | Silent | STAD |
| 354 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 354 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 440 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 563 | C → C | 0.001887 | SNP | Silent | UCEC |
| 576 | R → C | 0.002288 | SNP | Missense Mutation | STAD |