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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
B2RSH2 Gnai1 Guanine nucleotide-binding protein G(i) subunit … Mus musculus (Mouse) 354 aa

Protein Details: B2RSH2 (Gnai1)

Protein Information
AccessionB2RSH2
Protein NamesGuanine nucleotide-binding protein G(i) subunit alpha-1 (EC 3.6.5.-) (Adenylate cyclase-inhibiting G alpha protein)
Gene SymbolGnai1
OrganismMus musculus (Mouse)
Length354 aa
IsoformsNo isoforms
Related PMIDs 29575903 29733200 31311849 31772009 34200797 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGCTLSAEDK11AAVERSKMID21RNLREDGEKA31AREVKLLLLG41AGESGKSTIV
51-10051KQMKIIHEAG61YSEEECKQYK71AVVYSNTIQS81IIAIIRAMGR91LKIDFGDSAR
101-150101ADDARQLFVL111AGAAEEGFMT121AELAGVIKRL131WKDSGVQACF141NRSREYQLND
151-200151SAAYYLNDLD161RIAQPNYIPT171QQDVLRTRVK181TTGIVETHFT191FKDLHFKMFD
201-250201VGGQRSERKK211WIHCFEGVTA221IIFCVALSDY231DLVLAEDEEM241NRMHESMKLF
251-300251DSICNNKWFT261DTSIILFLNK271KDLFEEKIKK281SPLTICYPEY291AGSNTYEEAA
301-350301AYIQCQFEDL311NKRKDTKEIY321THFTCATDTK331NVQFVFDAVT341DVIIKNNLKD
351-354351CGLF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
3 -
brain (39008777)
-
GPS-Palm: 0.98
Deep-Palm: 0.04
66 G-protein alpha subunit
Brain (31311849)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.17
139 - -
Brain (35358180)
GPS-Palm: 0.82
Deep-Palm: 0.91
214 - - -
Deep-Palm: 0.77
224 - - -
Deep-Palm: 0.62
254 - -
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.32
286 - -
Brain (35358180)
GPS-Palm: 0.76
Deep-Palm: 0.89
305 - -
Brain (35358180)
GPS-Palm: 0.78
Deep-Palm: 0.59
325 G-protein alpha subunit
Brain (34200797)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.28
351 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
-
GPS-Palm: 0.97
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.417
5
Brain
Specificity: 0.122
5/5 (100.0%)
3
Raw 264.7
Specificity: 0.073
3/3 (100.0%)
2
Testis
Specificity: 0.049
2/2 (100.0%)
1
NSC
Specificity: 0.024
1/1 (100.0%)
1
Liver
Specificity: 0.024
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
29
Brain tissue (Mass)
Specificity: 0.707
29/56 (51.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine