Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
B3KPX4 HACL1; PHYH2; hCG_1811148 2-hydroxyacyl-CoA lyase (EC 4.1.2.63) Homo sapiens (Human) 337 aa

Protein Details: B3KPX4 (HACL1)

Protein Information
Accession B3KPX4
Protein Names 2-hydroxyacyl-CoA lyase (EC 4.1.2.63)
Gene Symbol HACL1; PHYH2; hCG_1811148
Organism Homo sapiens (Human)
Length 337 aa
Isoforms No isoforms
Related PMIDs 31251020
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
37
LNCaP cells
Specificity: 1.000
37/46 (80.4%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPDSNFAERS11EEQVSGAKVI21AQALKTQDVE31YIFGIVGIPV41TEIAIAAQQL
51-10051GIKYIGMRNE61QAVDICAEEL71GNNVKPAVTL81LGNIHAVTKQ91LLEELDKTPW
101-150101QYPPESKWWK111TLREKMKSNE121AASKELASKK131SLPMNYYTVF141YHVQEQLPRD
151-200151CFVVSEGANT161MDIGRTVLQN171YLPRHRLDAG181TFGTMGVGLG191FAIAAAVVAK
201-250201DRSPGQWIIC211VEGDSAFGFS221GMEVETICRY231NLPIILLVVN241NNGIYQGFDT
251-300251DTWKEMLKFQ261DATAVVPPMC271LLPNSHYEQV281MTAFGGKGYF291VQTPEELQKS
301-337301LRQSLADTTK311PSLINIMIEP321QATRKAQDFH331WLTRSNM
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
228 Prediction (Medium) - -
270 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
140 R → C 0.002506 SNP Missense Mutation COAD
166 C → C 0.001887 SNP Silent UCEC
183 S → C 0.002427 SNP Missense Mutation BLCA
223 G → C 0.001887 SNP Missense Mutation UCEC
289 F → C 0.002506 SNP Missense Mutation COAD
301 F → C 0.002545 SNP Missense Mutation GBM
392 C → C 0.001887 SNP Silent UCEC
432 F → C 0.005435 SNP Missense Mutation ESCA