Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B4DF00 | N/A | 2-oxoglutarate dehydrogenase complex component E1 … | Homo sapiens (Human) | 974 aa |
Protein Details: B4DF00
Protein Information
| Accession | B4DF00 |
|---|---|
| Protein Names | 2-oxoglutarate dehydrogenase complex component E1 (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase) |
| Gene Symbol | Not available |
| Organism | Homo sapiens (Human) |
| Length | 974 aa |
| Isoforms | No isoforms |
| Related PMIDs | 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MYCAWLENPK11SVHKSWDIFF21RNTNAGAPPG31TAYQSPLPLS41RGSLAAVAHA
51-10051QSLVEAQPNV61DKLVEDHLAV71QSLIRAYQVR81GHHIAKLDPL91GISCVNFDDA
101-150101PVTVSSNVDL111AVFKERLRML121TVGGFYGLDE131SDLDKVFHLP141TTTFIGGQES
151-200151ALPLREIIRR161LEMAYCQHIG171VEFMFINDLE181QCQWIRQKFE191TPGIMQFTNE
201-250201EKRTLLARLV211RSTRFEEFLQ221RKWSSEKRFG231LEGCEVLIPA241LKTIIDKSSE
251-300251NGVDYVIMGM261PHRGRLNVLA271SVIRKELEQI281FCQFGSKLEA291ADEGSGDVKY
301-350301HLGMYHRRIN311RVTDRNITLS321LVANPSHLEA331ADPVVMGKTK341AEQFYCGDTE
351-400351GKKVMSILLH361GDAAFAGQGI371VYETFHLSDL381PSYTTHGTVH391VVVNNQIGFT
401-450401TDPRMARSSP411YPTDVARVVN421APIFHVNSDD431PEAVMYVCKV441AAEWRSTFHK
451-500451DVVVDLVCYR461RNGHNEMDEP471MFTQPLMYKQ481IRKQKPVLQK491YAELLVSQGV
501-550501VNQPEYEEEI511SKYDKICEEA521FARSKDEKIL531HIKHWLDSPW541PGFFTLDGQP
551-600551RSMSCPSTGL561TEDILTHIGN571VASSVPVENF581TIHGGLSRIL591KTRGEMVKNR
601-650601TVDWALAEYM611AFGSLLKEGI621HIRLSGQDVE631RGTFSHRHHV641LHDQNVDKRT
651-700651CIPMNHLWPN661QAPYTVCNSS671LSEYGVLGFE681LGFAMASPNA691LVLWEAQFGD
701-750701FHNTAQCIID711QFICPGQAKW721VRQNGIVLLL731PHGMEGMGPE741HSSARPERFL
751-800751QMCNDDPDVL761PDLKEANFDI771NQLYDCNWVV781VNCSTPGNFF791HVLRRQILLP
801-850801FRKPLIIFTP811KSLLRHPEAR821SSFDEMLPGT831HFQRVIPEDG841PAAQNPENVK
851-900851RLLFCTGKVY861YDLTRERKAR871DMVGQVAITR881IEQLSPFPFD891LLLKEVQKYP
901-950901NAELAWCQEE911HKNQGYYDYV921KPRLRTTISR931AKPVWYAGRD941PAAAPATGNK
951-974951KTHLTELQRL961LDTAFDLDVF971KNFS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | 2-oxoglutarate dehydrogenase E1 component, N-terminal domain | - | - |
Deep-Palm: 0.01
|
|
| 94 | - | - | - |
Deep-Palm: 0.78
|
|
| 166 | - | - | - |
Deep-Palm: 0.70
|
|
| 182 | - | - | - |
Deep-Palm: 0.05
|
|
| 234 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
Deep-Palm: 0.97
|
|
| 282 | - | - | - |
Deep-Palm: 0.97
|
|
| 346 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.91
|
|
| 438 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
Unknown
(32651440)
|
Deep-Palm: 0.11
|
|
| 458 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
Deep-Palm: 0.38
|
|
| 517 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.61
|
|
| 555 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.77
|
|
| 651 | - | - | - |
Deep-Palm: 0.04
|
|
| 667 | - | - | - |
Deep-Palm: 0.58
|
|
| 707 | - | - | - |
Deep-Palm: 0.11
|
|
| 714 | - | - | - |
Deep-Palm: 0.11
|
|
| 753 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
Deep-Palm: 0.85
|
|
| 776 | - | - | - |
Deep-Palm: 0.06
|
|
| 783 | - | - | - |
Deep-Palm: 0.09
|
|
| 855 | - | - | - |
Deep-Palm: 0.96
|
|
| 907 | - | - | - |
Deep-Palm: 0.79
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
cerebral cortex
Specificity: 0.500
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.500
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.