Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B4DH65 | N/A | 2-oxoglutarate dehydrogenase complex component E1 … | Homo sapiens (Human) | 856 aa |
Protein Details: B4DH65
Protein Information
| Accession | B4DH65 |
|---|---|
| Protein Names | 2-oxoglutarate dehydrogenase complex component E1 (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase) |
| Gene Symbol | Not available |
| Organism | Homo sapiens (Human) |
| Length | 856 aa |
| Isoforms | No isoforms |
| Related PMIDs | 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLTVGGFYGL11DESDLDKVFH21LPTTTFIGGQ31ESALPLREII41RRLEMAYCQH
51-10051IGVEFMFIND61LEQCQWIRQK71FETPGIMQFT81NEEKRTLLAR91LVRSTRFEEF
101-150101LQRKWSSEKR111FGLEGCEVLI121PALKTIIDKS131SENGVDYVIM141GMPHRGRLNV
151-200151LANVIRKELE161QIFCQFDSKL171EAADEGSGDV181KYHLGMYHRR191INRVTDRNIT
201-250201LSLVANPSHL211EAADPVVMGK221TKAEQFYCGD231TEGKKVMSIL241LHGDAAFAGQ
251-300251GIVYETFHLS261DLPSYTTHGT271VHVVVNNQIG281FTTDPRMARS291SPYPTDVARV
301-350301VNAPIFHVNS311DDPEAVMYVC321KVAAEWRSTF331HKDVVVDLVC341YRRNGHNEMD
351-400351EPMFTQPLMY361KQIRKQKPVL371QKYAELLVSQ381GVVNQPEYEE391EISKYDKICE
401-450401EAFARSKDEK411ILHIKHWLDS421PWPGFFTLDG431QPRSMSCPST441GLTEDILTHI
451-500451GNVASSVPVE461NFTIHGGLSR471ILKTRGEMVK481NRTVDWALAE491YMAFGSLLKE
501-550501GIHIRLSGQD511VERGTFSHRH521HVLHDQNVDK531RTCIPMNHLW541PNQAPYTVCN
551-600551SSLSEYGVLG561FELGFAMASP571NALVLWEAQF581GDFHNTAQCI591IDQFICPGQA
601-650601KWVRQNGIVL611LLPHGMEGMG621PEHSSARPER631FLQMCNDDPD641VLPDLKEANF
651-700651DINQLYDCNW661VVVNCSTPGN671FFHVLRRQIL681LPFRKPLIIF691TPKSLLRHPE
701-750701ARSSFDEMLP711GTHFQRVIPE721DGPAAQNPEN731VKRLLFCTGK741VYYDLTRERK
751-800751ARDMVGQVAI761TRIEQLSPFP771FDLLLKEVQK781YPNAELAWCQ791EEHKNQGYYD
801-850801YVKPRLRTTI811SRAKPVWYAG821RDPAAAPATG831NKKTHLTELQ841RLLDTAFDLD
851-856851IFKNFS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 48 | Thiamin diphosphate-binding fold 2-oxoglutarate dehydrogenase E1 component | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.70
|
|
| 64 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.05
|
|
| 116 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.91
Deep-Palm: 0.97
|
|
| 164 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.81
Deep-Palm: 0.94
|
|
| 228 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.69
Deep-Palm: 0.91
|
|
| 320 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
Unknown
(32651440)
|
Deep-Palm: 0.11
|
|
| 340 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.87
Deep-Palm: 0.38
|
|
| 399 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.84
Deep-Palm: 0.61
|
|
| 437 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.78
Deep-Palm: 0.77
|
|
| 533 | - | - | - |
Deep-Palm: 0.04
|
|
| 549 | - | - | - |
Deep-Palm: 0.58
|
|
| 589 | - | - | - |
Deep-Palm: 0.11
|
|
| 596 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.11
|
|
| 635 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
Deep-Palm: 0.85
|
|
| 658 | - | - | - |
Deep-Palm: 0.06
|
|
| 665 | - | - | - |
Deep-Palm: 0.09
|
|
| 737 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.96
|
|
| 789 | - | - | - |
Deep-Palm: 0.79
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
cerebral cortex
Specificity: 0.500
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.500
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.