Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B4DIP2 | ERBIN | Erbin (Densin-180-like protein) (Erbb2-interacting protein) … | Homo sapiens (Human) | 610 aa |
Protein Details: B4DIP2 (ERBIN)
Protein Information
| Accession | B4DIP2 |
|---|---|
| Protein Names | Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2) |
| Gene Symbol | ERBIN |
| Organism | Homo sapiens (Human) |
| Length | 610 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 29575903 31251020 32651440 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTTKRSLFVR11LVPCRCLRGE21EETVTTLDYS31HCSLEQVPKE41IFTFEKTLEE
51-10051LYLDANQIEE61LPKQLFNCQS71LHKLSLPDND81LTTLPASIAN91LINLRELDVS
101-150101KNGIQEFPEN111IKNCKVLTIV121EASVNPISKL131PDGFSQLLNL141TQLYLNDAFL
151-200151EFLPANFGRL161TKLQILELRE171NQLKMLPKTM181NRLTQLERLD191LGSNEFTEVP
201-250201EVLEQLSGLK211EFWMDANRLT221FIPGFIGSLK231QLTYLDVSKN241NIEMVEEGIS
251-300251TCENLQDLLL261SSNSLQQLPE271TIGSLKNITT281LKIDENQLMY291LPDSIGGLIS
301-350301VEELDCSFNE311VEALPSSIGQ321LTNLRTFAAD331HNYLQQLPPE341IGSWKNITVL
351-400351FLHSNKLETL361PEEMGDMQKL371KVINLSDNRL381KNLPFSFTKL391QQLTAMWLSD
401-450401NQSMLSRSFN411SNFTTVSSFH421CGSSRDLHGS431QGSLALSVAD441RRGSGGHIFR
451-500451MPLSNGQMGQ461PLRPQANYSQ471IHHPPQASVA481RHPSREQLID491YLMLKVAHQP
501-550501PYTQPHCSPR511QGHELAKQEI521RVRVEKDPEL531GFSISGGVGG541RGNPFRPDDD
551-600551GIFVTRVQPE561GPASKLLQPG571DKIIQANGYS581FINIEHGQAV591SLLKTFQNTV
601-610601ELIIVREVSS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 14 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.96
Deep-Palm: 0.94
|
| 16 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.94
Deep-Palm: 0.94
|
| 32 | Synaptic Scaffolding LAP/MAGUK Families | - |
LNCaP
(31251020)
|
GPS-Palm: 0.72
Deep-Palm: 0.86
|
|
| 68 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.93
|
|
| 114 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.81
|
|
| 252 | - | - | - |
Deep-Palm: 0.75
|
|
| 306 | - | - | - |
Deep-Palm: 0.94
|
|
| 421 | - | - | - |
Deep-Palm: 0.85
|
|
| 507 | - | - | - |
Deep-Palm: 0.38
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
3
Jurkat T cell
Specificity: 0.375
3/3 (100.0%)
1
HeLa cell
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.125
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.