Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B4DT28 | HNRNPR; HNRPR; hCG_38907 | Heterogeneous nuclear ribonucleoprotein R (cDNA … | Homo sapiens (Human) | 494 aa |
Protein Details: B4DT28 (HNRNPR)
Protein Information
| Accession | B4DT28 |
|---|---|
| Protein Names | Heterogeneous nuclear ribonucleoprotein R (cDNA FLJ54544, highly similar to Heterogeneous nuclear ribonucleoprotein R) |
| Gene Symbol | HNRNPR; HNRPR; hCG_38907 |
| Organism | Homo sapiens (Human) |
| Length | 494 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.917
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
33
LNCaP cells
Specificity: 0.917
33/46 (71.7%)
2
PC3 cells
Specificity: 0.056
2/4 (50.0%)
1
HeLa cells
Specificity: 0.028
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKTYRQREKQ11GSKVQESTKG21PDEAKIKVFV31GKIPRDLYED41ELVPLFEKAG
51-10051PIWDLRLMMD61PLSGQNRGYA71FITFCGKEAA81QEAVKLCDSY91EIRPGKHLGV
101-150101CISVANNRLF111VGSIPKNKTK121ENILEEFSKV131TEGLVDVILY141HQPDDKKKNR
151-200151GFCFLEYEDH161KSAAQARRRL171MSGKVKVWGN181VVTVEWADPV191EEPDPEVMAK
201-250201VKVLFVRNLA211TTVTEEILEK221SFSEFGKLER231VKKLKDYAFV241HFEDRGAAVK
251-300251AMDEMNGKEI261EGEEIEIVLA271KPPDKKRKER281QAARQASRST291AYEDYYYHPP
301-350301PRMPPPIRGR311GRGGGRGGYG321YPPDYYGYED331YYDDYYGYDY341HDYRGGYEDP
351-400351YYGYDDGYAV361RGRGGGRGGR371GAPPPPRGRG381APPPRGRAGY391SQRGAPLGPP
401-450401RGSRGGRGGP411AQQQRGRGSR421GSRGNRGGNV431GGKRKADGYN441QPDSKRRQTN
451-494451NQQNWGSQPI461AQQPLQQGGD471YSGNYGYNND481NQEFYQDTYG491QQWK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 75 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | RNA recognition motif | - |
| 87 | Prediction (High) | - | - |
| 101 | Prediction (Medium) | - | - |
| 153 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | RNA recognition motif | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 37 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 232 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 232 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 464 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 483 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 559 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 583 | S → C | 0.012195 | SNP | Missense Mutation | MESO |