Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B4DUR8 | CCT3 | T-complex protein 1 subunit gamma | Homo sapiens (Human) | 500 aa |
Protein Details: B4DUR8 (CCT3)
Protein Information
| Accession | B4DUR8 |
|---|---|
| Protein Names | T-complex protein 1 subunit gamma |
| Gene Symbol | CCT3 |
| Organism | Homo sapiens (Human) |
| Length | 500 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 31251020 31382980 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.649
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.649
24/46 (52.2%)
4
Jurkat T cells
Specificity: 0.108
4/25 (16.0%)
4
PC3 cells
Specificity: 0.108
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.108
4/4 (100.0%)
1
U937 cells
Specificity: 0.027
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MMKMLLDPMG11GIVMTNDGNA21ILREIQVQHP31AAKSMIEISR41TQDEEVGDGT
51-10051TSVIILAGEM61LSVAEHFLEQ71QMHPTVVISA81YRKALDDMIS91TLKKISIPVD
101-150101ISDSDMMLNI111INSSITTKAI121SRWSSLACNI131ALDAVKMVQF141EENGRKEIDI
151-200151KKYARVEKIP161GGIIEDSCVL171RGVMINKDVT181HPRMRRYIKN191PRIVLLDSSL
201-250201EYKKGESQTD211IEITREEDFT221RILQMEEEYI231QQLCEDIIQL241KPDVVITEKG
251-300251ISDLAQHYLM261RANITAIRRV271RKTDNNRIAR281ACGARIVSRP291EELREDDVGT
301-350301GAGLLEIKKI311GDEYFTFITD321CKDPKACTIL331LRGASKEILS341EVERNLQDAM
351-400351QVCRNVLLDP361QLVPGGGASE371MAVAHALTEK381SKAMTGVEQW391PYRAVAQALE
401-450401VIPRTLIQNC411GASTIRLLTS421LRAKHTQENC431ETWGVNGETG441TLVDMKELGI
451-500451WEPLAVKLQT461YKTAVETAVL471LLRIDDIVSG481HKKKGDDQSR491QGGAPDAGQE
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 128 | Prediction (Medium) | - | - |
| 168 | Prediction (Low) | - | - |
| 282 | Prediction (Medium) | - | - |
| 321 | Prediction (Low) | - | - |
| 327 | Prediction (Medium) | - | - |
| 353 | Prediction (Medium) | - | - |
| 410 | CYSMODDB SWISSPALM DBPTM Prediction (High) | TCP-1/cpn60 chaperonin family | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 16 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 24 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 216 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 228 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 237 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 399 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |