Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B4DUR8 | CCT3 | T-complex protein 1 subunit gamma | Homo sapiens (Human) | 500 aa |
Protein Details: B4DUR8 (CCT3)
Protein Information
| Accession | B4DUR8 |
|---|---|
| Protein Names | T-complex protein 1 subunit gamma |
| Gene Symbol | CCT3 |
| Organism | Homo sapiens (Human) |
| Length | 500 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MMKMLLDPMG11GIVMTNDGNA21ILREIQVQHP31AAKSMIEISR41TQDEEVGDGT
51-10051TSVIILAGEM61LSVAEHFLEQ71QMHPTVVISA81YRKALDDMIS91TLKKISIPVD
101-150101ISDSDMMLNI111INSSITTKAI121SRWSSLACNI131ALDAVKMVQF141EENGRKEIDI
151-200151KKYARVEKIP161GGIIEDSCVL171RGVMINKDVT181HPRMRRYIKN191PRIVLLDSSL
201-250201EYKKGESQTD211IEITREEDFT221RILQMEEEYI231QQLCEDIIQL241KPDVVITEKG
251-300251ISDLAQHYLM261RANITAIRRV271RKTDNNRIAR281ACGARIVSRP291EELREDDVGT
301-350301GAGLLEIKKI311GDEYFTFITD321CKDPKACTIL331LRGASKEILS341EVERNLQDAM
351-400351QVCRNVLLDP361QLVPGGGASE371MAVAHALTEK381SKAMTGVEQW391PYRAVAQALE
401-450401VIPRTLIQNC411GASTIRLLTS421LRAKHTQENC431ETWGVNGETG441TLVDMKELGI
451-500451WEPLAVKLQT461YKTAVETAVL471LLRIDDIVSG481HKKKGDDQSR491QGGAPDAGQE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 128 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.88
Deep-Palm: 0.88
|
|
| 168 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.82
|
|
| 234 | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.78
|
|
| 282 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.97
|
|
| 321 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.91
|
|
| 327 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.89
Deep-Palm: 0.53
|
|
| 353 | - | - |
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.89
Deep-Palm: 0.97
|
|
| 410 | SWISSPALM DBPTM CYSMODDB | TCP-1/cpn60 chaperonin family | - |
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.94
Deep-Palm: 0.96
|
| 430 | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.86
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
cerebral cortex
Specificity: 0.364
4/4 (100.0%)
2
LNCaP
Specificity: 0.182
2/2 (100.0%)
1
U937 cell
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.364
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 16 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 24 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 216 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 228 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 237 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 399 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |