Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B4DV51 | RAN | GTP-binding nuclear protein Ran | Homo sapiens (Human) | 128 aa |
Protein Details: B4DV51 (RAN)
Protein Information
| Accession | B4DV51 |
|---|---|
| Protein Names | GTP-binding nuclear protein Ran |
| Gene Symbol | RAN |
| Organism | Homo sapiens (Human) |
| Length | 128 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 21076176 22496122 31251020 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.833
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.833
35/46 (76.1%)
4
Jurkat T cells
Specificity: 0.095
4/25 (16.0%)
2
DU145 cells
Specificity: 0.048
2/2 (100.0%)
1
Endothelial cells
Specificity: 0.024
1/2 (50.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MFDVTSRVTY11KNVPNWHRDL21VRVCENIPIV31LCGNKVDIKD41RKVKAKSIVF
51-10051HRKKNLQYYD61ISAKSNYNFE71KPFLWLARKL81IGDPNLEFVA91MPALAPPEVV
101-128101MDPALAAQYE111HDLEVAQTTA121LPDEDDDL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 24 | CYSMODDB SWISSPALM DBPTM | Ras family | - |
| 32 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Ras family | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 85 | C → C | 0.002033 | SNP | Silent | LUSC |