Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B4DXW1 | ACTR3 | Actin related protein 3 (cDNA … | Homo sapiens (Human) | 367 aa |
Protein Details: B4DXW1 (ACTR3)
Protein Information
| Accession | B4DXW1 |
|---|---|
| Protein Names | Actin related protein 3 (cDNA FLJ51148, highly similar to Actin-like protein 3) (cDNA FLJ52434, highly similar to Actin-like protein 3) (cDNA, FLJ79112, highly similar to Actin-like protein 3) (cDNA, FLJ79295, highly similar to Actin-like protein 3) |
| Gene Symbol | ACTR3 |
| Organism | Homo sapiens (Human) |
| Length | 367 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.786
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
22
LNCaP cells
Specificity: 0.786
22/46 (47.8%)
4
PC3 cells
Specificity: 0.143
4/4 (100.0%)
2
Cerebral cortex
Specificity: 0.071
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKGVDDLDFF11IGDEAIEKPT21YATKWPIRHG31IVEDWDLMER41FMEQVIFKYL
51-10051RAEPEDHYFL61LTEPPLNTPE71NREYTAEIMF81ESFNVPGLYI91AVQAVLALAA
101-150101SWTSRQVGER111TLTGTVIDSG121DGVTHVIPVA131EGYVIGSCIK141HIPIAGRDIT
151-200151YFIQQLLRDR161EVGIPPEQSL171ETAKAVKERY181SYVCPDLVKE191FNKYDTDGSK
201-250201WIKQYTGINA211ISKKEFSIDV221GYERFLGPEI231FFHPEFANPD241FTQPISEVVD
251-300251EVIQNCPIDV261RRPLYKNIVL271SGGSTMFRDF281GRRLQRDLKR291TVDARLKLSE
301-350301ELSGGRLKPK311PIDVQVITHH321MQRYAVWFGG331SMLASTPEFY341QVCHTKKDYE
351-367351EIGPSICRHN361PVFGVMS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 138 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Actin | - |
| 184 | Prediction (Medium) | - | - |
| 256 | Prediction (Low) | - | - |
| 343 | Prediction (Low) | - | - |
| 357 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 34 | C → C | 0.001887 | SNP | Splice Region | UCEC |
| 230 | R → C | 0.007299 | SNP | Missense Mutation | READ |