Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B4E2Q0 | ATP2C1; hCG_14809 | Calcium-transporting ATPase (EC 7.2.2.10) | Homo sapiens (Human) | 953 aa |
Protein Details: B4E2Q0 (ATP2C1)
Protein Information
| Accession | B4E2Q0 |
|---|---|
| Protein Names | Calcium-transporting ATPase (EC 7.2.2.10) |
| Gene Symbol | ATP2C1; hCG_14809 |
| Organism | Homo sapiens (Human) |
| Length | 953 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.900
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.900
36/46 (78.3%)
3
PC3 cells
Specificity: 0.075
3/4 (75.0%)
1
HeLa cells
Specificity: 0.025
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDSLLPPSRF11SYFKKYPLHA21IRRYLSTLRN31QRAEEQVARF41QKIPNGENET
51-10051MIPVLTSKKA61SELPVSEVAS71ILQADLQNGL81NKCEVSHRRA91FHGWNEFDIS
101-150101EDEPLWKKYI111SQFKNPLIML121LLASAVISVL131MHQFDDAVSI141TVAILIVVTV
151-200151AFVQEYRSEK161SLEELSKLVP171PECHCVREGK181LEHTLARDLV191PGDTVCLSVG
201-250201DRVPADLRLF211EAVDLSIDES221SLTGETTPCS231KVTAPQPAAT241NGDLASRSNI
251-300251AFMGTLVRCG261KAKGVVIGTG271ENSEFGEVFK281MMQAEEAPKT291PLQKSMDLLG
301-350301KQLSFYSFGI311IGIIMLVGWL321LGKDILEMFT331ISVSLAVAAI341PEGLPIVVTV
351-400351TLALGVMRMV361KKRAIVKKLP371IVETLGCCNV381ICSDKTGTLT391KNEMTVTHIF
401-450401TSDGLHAEVT411GVGYNQFGEV421IVDGDVVHGF431YNPAVSRIVE441AGCVCNDAVI
451-500451RNNTLMGKPT461EGALIALAMK471MGLDGLQQDY481IRKAEYPFSS491EQKWMAVKCV
501-550501HRTQQDRPEI511CFMKGAYEQV521IKYCTTYQSK531GQTLTLTQQQ541RDVYQQEKAR
551-600551MGSAGLRVLA561LASGPELGQL571TFLGLVGIID581PPRTGVKEAV591TTLIASGVSI
601-650601KMITGDSQET611AVAIASRLGL621YSKTSQSVSG631EEIDAMDVQQ641LSQIVPKVAV
651-700651FYRASPRHKM661KIIKSLQKNG671SVVAMTGDGV681NDAVALKAAD691IGVAMGQTGT
701-750701DVCKEAADMI711LVDDDFQTIM721SAIEEGKGIY731NNIKNFVRFQ741LSTSIAALTL
751-800751ISLATLMNFP761NPLNAMQILW771INIIMDGPPA781QSLGVEPVDK791DVIRKPPRNW
801-850801KDSILTKNLI811LKILVSSIII821VCGTLFVFWR831ELRDNVITPR841DTTMTFTCFV
851-900851FFDMFNALSS861RSQTKSVFEI871GLCSNRMFCY881AVLGSIMGQL891LVIYFPPLQK
901-950901VFQTESLSIL911DLLFLLGLTS921SVCIVAEIIK931KVERSREKIQ941KHVSSTSSSF
951-953951LEV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 83 | Prediction (Low) | - | - |
| 173 | Prediction (Medium) | - | - |
| 175 | Prediction (High) | - | - |
| 196 | Prediction (Medium) | - | - |
| 259 | Prediction (Medium) | - | - |
| 377 | Prediction (High) | - | - |
| 378 | Prediction (High) | - | - |
| 382 | Prediction (Medium) | - | - |
| 443 | Prediction (Medium) | - | - |
| 445 | Prediction (Medium) | - | - |
| 524 | Prediction (Low) | - | - |
| 822 | Prediction (Medium) | - | - |
| 873 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Cation transporting ATPase C-terminus | 29575903 |
| 879 | Prediction (Medium) | - | - |
| 923 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 143 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 195 | C → Vfs*4 | 0.001014 | DEL | Frame Shift Del | BRCA |
| 409 | C → C | 0.002506 | SNP | Silent | COAD |
| 490 | C → Y | 0.001969 | SNP | Missense Mutation | HNSC |
| 760 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 814 | C → C | 0.002288 | SNP | Silent | STAD |
| 972 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |