Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B5BU24 | YWHAB | 14-3-3 protein beta/alpha | Homo sapiens (Human) | 246 aa |
Protein Details: B5BU24 (YWHAB)
Protein Information
| Accession | B5BU24 |
|---|---|
| Protein Names | 14-3-3 protein beta/alpha |
| Gene Symbol | YWHAB |
| Organism | Homo sapiens (Human) |
| Length | 246 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTMDKSELVQ11KAKLAEQAER21YDDMAAAMKA31VTEQGHELSN41EERNLLSVAY
51-10051KNVVGARRSS61WRVISSIEQK71TERNEKKQQM81GKEYREKIEA91ELQDICNDVL
101-150101ELLDKYLIPN111ATQPESKVFY121LKMKGDYFRY131LSEVASGDNK141QTTVSNSQQA
151-200151YQEAFEISKK161EMQPTHPIRL171GLALNFSVFY181YEILNSPEKA191CSLAKMAFDE
201-246201AIAELDTLNE211ESYKDSTLIM221QLLRDNLTLW231TSENQGDEGD241AGEGEN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 96 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.70
Deep-Palm: 0.95
|
|
| 191 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.77
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
PC3
Specificity: 0.444
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.444
4/4 (100.0%)
1
Jurkat T cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 57 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 62 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 85 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 169 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 169 | R → C | 0.005660 | SNP | Missense Mutation | UCEC |