Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B5MCR8 | SLC30A6 | Solute carrier family 30 (Zinc … | Homo sapiens (Human) | 387 aa |
Protein Details: B5MCR8 (SLC30A6)
Protein Information
| Accession | B5MCR8 |
|---|---|
| Protein Names | Solute carrier family 30 (Zinc transporter), member 6, isoform CRA_b (Solute carrier family 30 member 6) |
| Gene Symbol | SLC30A6 |
| Organism | Homo sapiens (Human) |
| Length | 387 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTCLISYWVT11LRKPSPVYSF21GFERLEVLAV31FASTVLAQLG41ALFILKESAE
51-10051RFLEQPEIHT61GRLLVGTFVA71LCFNLFTMLS81IRNKPFAYVS91EAASTSWLQE
101-150101HVADLSRSLC111GIIPGLSSIF121LPRMNPFVLI131DLAGAFALCI141TYMLIEINNY
151-200151FAVDTASAIA161IALMTFGTMY171PMSVYSGKVL181LQTTPPHVIG191QLDKLIREVS
201-250201TLDGVLEVRN211EHFWTLGFGS221LAGSVHVRIR231RDANEQMVLA241HVTNRLYTLV
251-300251STLTVQIFKD261DWIRPALLSG271PVAANVLNFS281DHHVIPMPLL291KGTDDLNPVT
301-350301STPAKPSSPP311PEFSFNTPGK321NVNPVILLNT331QTRPYGFGLN341HGHTPYSSML
351-387351NQGLGVPGIG361ATQGLRTGFT371NIPSRYGTNN381RIGQPRP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
|
| 72 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.93
|
|
| 110 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.95
|
| 139 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.08
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
LNCaP
Specificity: 0.800
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.200
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 125 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 152 | M → Cfs*47 | 0.003460 | DEL | Frame Shift Del | CESC |
| 216 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 336 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 410 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |