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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
B5MDF5 RAN; hCG_1744585 GTP-binding nuclear protein Ran Homo sapiens (Human) 233 aa

Protein Details: B5MDF5 (RAN)

Protein Information
Accession B5MDF5
Protein Names GTP-binding nuclear protein Ran
Gene Symbol RAN; hCG_1744585
Organism Homo sapiens (Human)
Length 233 aa
Isoforms No isoforms
Related PMIDs 19801377 21076176 22496122 31251020 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.761
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.761
35/46 (76.1%)
4
Jurkat T cells
Specificity: 0.087
4/25 (16.0%)
4
Cerebral cortex
Specificity: 0.087
4/4 (100.0%)
2
DU145 cells
Specificity: 0.043
2/2 (100.0%)
1
Endothelial cells
Specificity: 0.022
1/2 (50.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAQGEPQVQ11FKLVLVGDGG21TGKTTFVKRH31LTGEFEKKYV41ATLGVEVHPL
51-10051VFHTNRGPIK61FNVWDTAGQE71KFGGLRDGYY81IQEMGIHHVA91HAGLELMSSA
101-150101QCAIIMFDVT111SRVTYKNVPN121WHRDLVRVCE131NIPIVLCGNK141VDIKDRKVKA
151-200151KSIVFHRKKN161LQYYDISAKS171NYNFEKPFLW181LARKLIGDPN191LEFVAMPALA
201-233201PPEVVMDPAL211AAQYEHDLEV221AQTTALPDED231DDL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
129 CYSMODDB SWISSPALM DBPTM Ras family -
137 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Ras family -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
85 C → C 0.002033 SNP Silent LUSC