Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B7Z4L4 | RPN1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | Homo sapiens (Human) | 435 aa |
Protein Details: B7Z4L4 (RPN1)
Protein Information
| Accession | B7Z4L4 |
|---|---|
| Protein Names | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 |
| Gene Symbol | RPN1 |
| Organism | Homo sapiens (Human) |
| Length | 435 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.837
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.837
36/46 (78.3%)
4
Jurkat T cells
Specificity: 0.093
4/25 (16.0%)
3
PC3 cells
Specificity: 0.070
3/4 (75.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRVKLASRNV11ESYTKLGNPT21RSEDLLDYGP31FRDVPAYSQD41TFKVHYENNS
51-10051PFLTITSMTR61VIEVSHWGNI71AVEENVDLKH81TGAVLKGPFS91RYDYQRQPDS
101-150101GISSIRSFKT111ILPAAAQDVY121YRDEIGNVST131SHLLILDDSV141EMEIRPRFPL
151-200151FGGWKTHYIV161GYNLPSYEYL171YNLGDQYALK181MRFVDHVFDE191QVIDSLTVKI
201-250201ILPEGAKNIE211IDSPYEISRA221PDELHYTYLD231TFGRPVIVAY241KKNLVEQHIQ
251-300251DIVVHYTFNK261VLMLQEPLLV271VAAFYILFFT281VIIYVRLDFS291ITKDPAAEAR
301-350301MKVACITEQV311LTLVNKRIGL321YRHFDETVNR331YKQSRDISTL341NSGKKSLETE
351-400351HKALTSEIAL361LQSRLKTEGS371DLCDRVSEMQ381KLDAQVKELV391LKSAVEAERL
401-435401VAGKLKKDTY411IENEKLISGK421RQELVTKIDH431ILDAL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 305 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 373 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 101 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 263 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 406 | R → C | 0.001969 | SNP | Missense Mutation | LGG |