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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
B7Z645 SYNCRIP; hCG_401112 Heterogeneous nuclear ribonucleoprotein Q (Synaptotagmin … Homo sapiens (Human) 464 aa

Protein Details: B7Z645 (SYNCRIP)

Protein Information
Accession B7Z645
Protein Names Heterogeneous nuclear ribonucleoprotein Q (Synaptotagmin binding cytoplasmic RNA interacting protein) (Synaptotagmin binding, cytoplasmic RNA interacting protein, isoform CRA_b)
Gene Symbol SYNCRIP; hCG_401112
Organism Homo sapiens (Human)
Length 464 aa
Isoforms No isoforms
Related PMIDs 29575903 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 0.600
3/4 (75.0%)
1
HeLa cells
Specificity: 0.200
1/1 (100.0%)
1
Cerebral cortex
Specificity: 0.200
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKTYRQREKQ11GTKVADSSKG21PDEAKIKALL31ERTGYTLDVT41TGQRKYGGPP
51-10051PDSVYSGQQP61SVGTEIFVGK71IPRDLFEDEL81VPLFEKAGPI91WDLRLMMDPL
101-150101TGLNRGYAFV111TFCTKEAAQE121AVKLYNNHEI131RSGKHIGVCI141SVANNRLFVG
151-200151SIPKSKTKEQ161ILEEFSKVTE171GLTDVILYHQ181PDDKKKNRGF191CFLEYEDHKT
201-250201AAQARRRLMS211GKVKVWGNVG221TVEWADPIED231PDPEVMAKVK241VLFVRNLANT
251-300251VTEEILEKAF261SQFGKLERVK271KLKDYAFIHF281DERDGAVKAM291EEMNGKDLEG
301-350301ENIEIVFAKP311PDQKRKERKA321QRQAAKNQMY331DDYYYYGPPH341MPPPTRGRGR
351-400351GGRGGYGYPP361DYYGYEDYYD371YYGYDYHNYR381GGYEDPYYGY391EDFQVGARGR
401-450401GGRGARGAAP411SRGRGAAPPR421GRAGYSQRGG431PGSARGVRGA441RGGAQQQRGR
451-464451GQGKGVEAGP461DLLQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
113 CYSMODDB SWISSPALM DBPTM Prediction (Medium) RNA recognition motif -
139 Prediction (Medium) - -
191 CYSMODDB SWISSPALM DBPTM Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
55 S → delinsRRCI 0.002033 INS In Frame Ins LUSC
229 R → C 0.002288 SNP Missense Mutation STAD
229 R → C 0.002141 SNP Missense Mutation SKCM
229 R → C 0.001887 SNP Missense Mutation UCEC
276 Y → C 0.001887 SNP Missense Mutation UCEC
304 R → C 0.002288 SNP Missense Mutation STAD
358 F → C 0.001887 SNP Missense Mutation UCEC
448 R → C 0.003774 SNP Missense Mutation UCEC
460 Y → C 0.001887 SNP Missense Mutation UCEC
469 Y → C 0.002294 SNP Missense Mutation OV
548 R → C 0.002506 SNP Missense Mutation COAD
548 R → C 0.002141 SNP Missense Mutation SKCM