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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
B7Z934 EBF2 Transcription factor COE1 (Early B-cell … Homo sapiens (Human) 427 aa

Protein Details: B7Z934 (EBF2)

Protein Information
AccessionB7Z934
Protein NamesTranscription factor COE1 (Early B-cell factor)
Gene SymbolEBF2
OrganismHomo sapiens (Human)
Length427 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MCRVLLTHEV11MCSRCCEKKS21CGNRNETPSD31PVIIDRFFLK41FFLKCNQNCL
51-10051KTAGNPRDMR61RFQVVLSTTV71NVDGHVLAVS81DNMFVHNNSK91HGRRARRLDP
101-150101SEATPCIKAI111SPSEGWTTGG121AMVIIIGDNF131FDGLQVVFGT141MLVWSELITP
151-200151HAIRVQTPPR161HIPGVVEVTL171SYKSKQFCKG181APGRFIYTAL191NEPTIDYGFQ
201-250201RLQKVIPRHP211GDPERLAKEM221LLKRAADLVE231ALYGTPHNNQ241DIILKRAADI
251-300251AEALYSVPRN261PSQLPALSSS271PAHSGMMGIN281SYGSQLGVSI291SESTQGNNQG
301-350301YIRNTSSISP311RGYSSSSTPQ321QSNYSTSSNS331MNGYSNVPMA341NLGVPGSPGF
351-400351LNGSPTGSPY361GIMSSSPTVG371SSSTSSILPF381SSSVFPAVKQ391KSAFAPVIRP
401-427401QGSPSPACSS411GNGNGFRAMT421GLVVPPM
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
2 Transcription factor COE Transcription factor COE, DNA-binding domain superfamily Transcription factor COE, DNA-binding domain - -
GPS-Palm: 0.91
Deep-Palm: 0.01
12 SWISSPALM DBPTM CYSMODDB Transcription factor COE, conserved site Transcription factor COE1 DNA-binding domain Transcription factor COE Transcription factor COE, DNA-binding domain Transcription factor COE, DNA-binding domain superfamily - -
GPS-Palm: 0.77
Deep-Palm: 0.02
15 Transcription factor COE, conserved site Transcription factor COE, DNA-binding domain superfamily Transcription factor COE Transcription factor COE, DNA-binding domain - -
Deep-Palm: 0.13
16 Transcription factor COE, conserved site Transcription factor COE, DNA-binding domain superfamily Transcription factor COE, DNA-binding domain Transcription factor COE - -
Deep-Palm: 0.17
21 Transcription factor COE, conserved site Transcription factor COE, DNA-binding domain superfamily Transcription factor COE Transcription factor COE, DNA-binding domain - -
Deep-Palm: 0.12
45 Transcription factor COE, DNA-binding domain Transcription factor COE, DNA-binding domain superfamily Transcription factor COE - -
GPS-Palm: 0.82
Deep-Palm: 0.58
49 Transcription factor COE Transcription factor COE, DNA-binding domain superfamily Transcription factor COE, DNA-binding domain - -
GPS-Palm: 0.78
Deep-Palm: 0.59
106 - - -
GPS-Palm: 0.67
Deep-Palm: 0.94
178 - - -
GPS-Palm: 0.87
Deep-Palm: 0.91
408 - - -
Deep-Palm: 0.90
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
78 G → C 0.001764 SNP Missense Mutation LUAD
150 C → Y 0.002288 SNP Missense Mutation STAD
164 C → C 0.005618 SNP Silent PAAD
193 C → G 0.003559 SNP Missense Mutation KIRP
254 C → Lfs*6 0.002288 INS Frame Shift Ins STAD
312 G → C 0.001887 SNP Missense Mutation UCEC
462 S → C 0.001764 SNP Missense Mutation LUAD
462 S → C 0.002033 SNP Missense Mutation LUSC