Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| B7ZKQ9 | SCARB1 | Scavenger receptor class B member … | Homo sapiens (Human) | 481 aa |
Protein Details: B7ZKQ9 (SCARB1)
Protein Information
| Accession | B7ZKQ9 |
|---|---|
| Protein Names | Scavenger receptor class B member 1 (SR-BI) |
| Gene Symbol | SCARB1 |
| Organism | Homo sapiens (Human) |
| Length | 481 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 29575903 31251020 31382980 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.826
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
38
LNCaP cells
Specificity: 0.826
38/46 (82.6%)
4
PC3 cells
Specificity: 0.087
4/4 (100.0%)
2
DU145 cells
Specificity: 0.043
2/2 (100.0%)
1
U937 cells
Specificity: 0.022
1/1 (100.0%)
1
HeLa cells
Specificity: 0.022
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGCSAKARWA11AGALGVAGLL21CAVLGAVMIV31MVPSLIKQQV41LKNVRIDPSS
51-10051LSFNMWKEIP61IPFYLSVYFF71DVMNPSEILK81GEKPQVRERG91PYVYREFRHK
101-150101SNITFNNNDT111VSFLEYRTFQ121FQPSKSHGSE131SDYIVMPNIL141VLGAAVMMEN
151-200151KPMTLKLIMT161LAFTTLGERA171FMNRTVGEIM181WGYKDPLVNL191INKYFPGMFP
201-250201FKDKFGLFAE211LNNSDSGLFT221VFTGVQNISR231IHLVDKWNGL241SKVDFWHSDQ
251-300251CNMINGTSGQ261MWPPFMTPES271SLEFYSPEAC281RSMKLMYKES291GVFEGIPTYR
301-350301FVAPKTLFAN311GSIYPPNEGF321CPCLESGIQN331VSTCRFSAPL341FLSHPHFLNA
351-400351DPVLAEAVTG361LHPNQEAHSL371FLDIHPVTGI381PMNCSVKLQL391SLYMKSVAGI
401-450401GQTGKIEPVV411LPLLWFAESG421AMEGETLHTF431YTQLVLMPKE441KCYLFWSSSK
451-481451KGSKDKEAIQ461AYSESLMTSA471PKGSVLQEAK481L
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 3 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 280 | Prediction (Low) | - | - |
| 334 | Prediction (Low) | - | - |
| 384 | Prediction (Low) | - | - |
| 442 | Experimental Prediction (Medium) | - | 29575903 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 45 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 45 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 246 | W → C | 0.002288 | SNP | Missense Mutation | STAD |
| 300 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 323 | C → C | 0.002506 | SNP | Silent | COAD |
| 453 | C → F | 0.002033 | SNP | Missense Mutation | LUSC |
| 462 | C → Y | 0.008130 | SNP | Missense Mutation | THYM |