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UniProt ID Gene Symbol Protein Name Organism Length Action
B9VP19 HSPD1 60 kDa heat shock protein, … Homo sapiens (Human) 184 aa

Protein Details: B9VP19 (HSPD1)

Protein Information
AccessionB9VP19
Protein Names60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (Heat shock protein 60)
Gene SymbolHSPD1
OrganismHomo sapiens (Human)
Length184 aa
IsoformsNo isoforms
Related PMIDs 21076176 22496122 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501ATVLARSIAK11EGIEKISKGA21NPVEIRRGVM31LVVDAVIAEL41KKQSKPVTTP
51-10051EEIAQVATIS61ANGDKEIGNI71SDAMKKVGRK81GVITVKDGKT91LNDELEIIEG
101-150101IKFDRGYISP111YFINTSKGQK121CEFQDAYVLL131SEKKISSVQS141VVPALEIANA
151-184151HRKPLVIIAE161DVDGEALSTL171VLNRLKVGLQ181DVAI
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
121 - -
LNCaP (31251020)
Unknown (32651440)
Deep-Palm: 0.55
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
cerebral cortex
Specificity: 0.667
4/4 (100.0%)
1
Jurkat T cell
Specificity: 0.167
1/1 (100.0%)
1
EC cell
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
362 G → C 0.001014 SNP Missense Mutation BRCA
370 R → C 0.002506 SNP Missense Mutation COAD
370 R → C 0.002020 SNP Missense Mutation PRAD
370 R → C 0.003774 SNP Missense Mutation UCEC