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UniProt ID Gene Symbol Protein Name Organism Length Action
B9VP24 HSPD1 60 kDa heat shock protein, … Homo sapiens (Human) 185 aa

Protein Details: B9VP24 (HSPD1)

Protein Information
AccessionB9VP24
Protein Names60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (Heat shock protein 60)
Gene SymbolHSPD1
OrganismHomo sapiens (Human)
Length185 aa
IsoformsNo isoforms
Related PMIDs 21076176 22496122
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501ATVLACSIAK11EGFEKISKGA21NPVEIRRGVM31LAVDAVIAEP41KKQSKPVTTP
51-10051EEIAQVATIS61ASGDKEIGHI71LSDAVKKVGR81KGVITVKDGK91TLNDGLEIIE
101-150101SLKFDRGYVS111PYFINTSKGQ121KCEFQEAYVL131LSEKKISSVQ141SIVPALETAS
151-185151AHRKPLVIIT161EDVGGEALST171LVLNSLKIDF181QVVAV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 - - -
Deep-Palm: 0.15
122 - - -
Deep-Palm: 0.68
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
Jurkat T cell
Specificity: 0.500
1/1 (100.0%)
1
EC cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
362 G → C 0.001014 SNP Missense Mutation BRCA
370 R → C 0.002506 SNP Missense Mutation COAD
370 R → C 0.002020 SNP Missense Mutation PRAD
370 R → C 0.003774 SNP Missense Mutation UCEC