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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
C9J611 TM4SF1 Transmembrane 4 L six family … Homo sapiens (Human) 117 aa

Protein Details: C9J611 (TM4SF1)

Protein Information
AccessionC9J611
Protein NamesTransmembrane 4 L six family member 1
Gene SymbolTM4SF1
OrganismHomo sapiens (Human)
Length117 aa
IsoformsNo isoforms
Related PMIDs 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLSSVLAALI11GIAGSGYCVI21VAALGLAEGP31LCLDSLGQWN41YTFASTEGQY
51-10051LLDTSTWSEC61TEPKHIVEWN71VSLFSILLAL81GGIEFILCLI91QVINGVLGGI
101-117101CGFCCSHQQV111RTCMKMS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
18 SWISSPALM DBPTM CYSMODDB L6 membrane L6 membrane protein - -
GPS-Palm: 0.74
Deep-Palm: 0.97
32 SWISSPALM DBPTM CYSMODDB L6 membrane L6 membrane protein
HeLa (29575903)
-
Deep-Palm: 0.96
60 SWISSPALM DBPTM CYSMODDB L6 membrane protein
HeLa (29575903)
-
Deep-Palm: 0.45
88 - - -
Deep-Palm: 0.97
101 - - -
GPS-Palm: 0.79
Deep-Palm: 0.21
104 - - -
Deep-Palm: 0.08
105 - - -
GPS-Palm: 0.80
Deep-Palm: 0.02
113 - - -
GPS-Palm: 0.89
Deep-Palm: 0.01
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
PC3
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
21 C → F 0.002506 SNP Missense Mutation COAD
21 C → S 0.002294 SNP Missense Mutation OV
29 Y → C 0.001887 SNP Missense Mutation UCEC
77 G → C 0.001887 SNP Missense Mutation UCEC
84 C → G 0.001764 SNP Missense Mutation LUAD
84 C → Wfs*39 0.004219 DEL Frame Shift Del SARC
107 C → S 0.001764 SNP Missense Mutation LUAD
? ? → ? 0.001887 SNP Missense Mutation UCEC