Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| C9J6E1 | PLSCR4 | Phospholipid scramblase | Homo sapiens (Human) | 262 aa |
Protein Details: C9J6E1 (PLSCR4)
Protein Information
| Accession | C9J6E1 |
|---|---|
| Protein Names | Phospholipid scramblase |
| Gene Symbol | PLSCR4 |
| Organism | Homo sapiens (Human) |
| Length | 262 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 1.000
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSGVVPTAPE11QPAGEMENQT21KPPDPRPDAP31PEYNSHFLPG41PPGTAVPPPT
51-10051GYPGGLPMGY61YSPQQPSTFP71LYQPVGGIHP81VRYQPGKYPM91PNQSVPITWM
101-150101PGPTPMANCP111PGLEYLVQLD121NIHVLQHFEP131LEMMTCFETN141NRYDIKNNSD
151-200151QMVYIVTEDT161DDFTRNAYRT171LRPFVLRVTD181CMGREIMTMQ191RPFRCTCCCF
201-250201CCPSARQELE211VQCPPGVTIG221FVAEHWNLCR231AVYSIQNEKK241ENVMRVRGPC
251-262251STYGCGSDSV261FE
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 181 | Prediction (Medium) | - | - |
| 195 | Prediction (Medium) | - | - |
| 197 | Prediction (High) | - | - |
| 198 | Prediction (High) | - | - |
| 199 | Prediction (High) | - | - |
| 201 | Prediction (High) | - | - |
| 202 | Prediction (High) | - | - |
| 229 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Scramblase | - |
| 250 | Prediction (Low) | - | - |
| 255 | Prediction (Medium) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 195 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 204 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 247 | R → C | 0.002033 | SNP | Missense Mutation | THCA |
| 247 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 250 | C → S | 0.002033 | SNP | Missense Mutation | LUSC |
| 312 | C → Lfs*5 | 0.002545 | INS | Frame Shift Ins | GBM |
| 327 | R → C | 0.002506 | SNP | Missense Mutation | COAD |