Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| C9J6E1 | PLSCR4 | Phospholipid scramblase | Homo sapiens (Human) | 262 aa |
Protein Details: C9J6E1 (PLSCR4)
Protein Information
| Accession | C9J6E1 |
|---|---|
| Protein Names | Phospholipid scramblase |
| Gene Symbol | PLSCR4 |
| Organism | Homo sapiens (Human) |
| Length | 262 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGVVPTAPE11QPAGEMENQT21KPPDPRPDAP31PEYNSHFLPG41PPGTAVPPPT
51-10051GYPGGLPMGY61YSPQQPSTFP71LYQPVGGIHP81VRYQPGKYPM91PNQSVPITWM
101-150101PGPTPMANCP111PGLEYLVQLD121NIHVLQHFEP131LEMMTCFETN141NRYDIKNNSD
151-200151QMVYIVTEDT161DDFTRNAYRT171LRPFVLRVTD181CMGREIMTMQ191RPFRCTCCCF
201-250201CCPSARQELE211VQCPPGVTIG221FVAEHWNLCR231AVYSIQNEKK241ENVMRVRGPC
251-262251STYGCGSDSV261FE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 109 | - | - | - |
Deep-Palm: 0.17
|
|
| 136 | - | - | - |
Deep-Palm: 0.06
|
|
| 181 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.95
|
|
| 195 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.37
|
|
| 197 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.60
|
|
| 198 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.50
|
|
| 199 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.08
|
|
| 201 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.13
|
|
| 202 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.08
|
|
| 213 | - | - | - |
Deep-Palm: 0.76
|
|
| 229 | SWISSPALM DBPTM CYSMODDB | Scramblase |
HeLa
(29575903)
| - |
GPS-Palm: 0.79
Deep-Palm: 0.82
|
| 250 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.10
|
|
| 255 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
PC3
Specificity: 0.500
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.500
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 195 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 204 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 247 | R → C | 0.002033 | SNP | Missense Mutation | THCA |
| 247 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 250 | C → S | 0.002033 | SNP | Missense Mutation | LUSC |
| 312 | C → Lfs*5 | 0.002545 | INS | Frame Shift Ins | GBM |
| 327 | R → C | 0.002506 | SNP | Missense Mutation | COAD |