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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
C9J7K9 PLSCR1 Phospholipid scramblase Homo sapiens (Human) 311 aa

Protein Details: C9J7K9 (PLSCR1)

Protein Information
AccessionC9J7K9
Protein NamesPhospholipid scramblase
Gene SymbolPLSCR1
OrganismHomo sapiens (Human)
Length311 aa
IsoformsNo isoforms
Related PMIDs 29575903 32651440 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNASHPETNL11PVGYPPQYPP21TAFQGPPGYS31GYPGPQVSYP41PPPAGHSGPG
51-10051PAGFPVPNQP61VYNQPVYNQP71VGAAGVPWMP81APQPPLNCPP91GLEYLSQIDQ
101-150101ILIHQQIELL111EVLTGFETNN121KYEIKNSFGQ131RVYFAAEDTD141CCTRNCCGPS
151-200151RPFTLRIIDN161MGQEVITLER171PLRCSSCCCP181CCLQEIEIQA191PPGVPIGYVI
201-250201QTWHPCLPKF211TIQNEKREDV221LKISGPCVVC231SCCGDVDFEI241KSLDEQCVVG
251-300251KISKHWTGIL261REAFTDADNF271GIQFPLDLDV281KMKAVMIGAC291FLIDFMFFES
301-311301TGSQEQKSGV311W
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
88 - - -
Deep-Palm: 0.77
141 SWISSPALM DBPTM CYSMODDB Scramblase
HeLa (29575903)
cerebral cortex (36430497)
GPS-Palm: 0.91
Deep-Palm: 0.66
142 SWISSPALM DBPTM CYSMODDB Scramblase
HeLa (29575903)
cerebral cortex (36430497)
GPS-Palm: 0.92
Deep-Palm: 0.80
146 SWISSPALM DBPTM CYSMODDB Scramblase
HeLa (29575903)
-
GPS-Palm: 0.81
Deep-Palm: 0.08
147 SWISSPALM DBPTM CYSMODDB Scramblase
HeLa (29575903)
-
GPS-Palm: 0.86
Deep-Palm: 0.17
174 - - -
GPS-Palm: 0.91
Deep-Palm: 0.78
177 - - -
GPS-Palm: 0.96
Deep-Palm: 0.46
178 - - -
GPS-Palm: 0.96
Deep-Palm: 0.44
179 - - -
GPS-Palm: 0.96
Deep-Palm: 0.45
181 - - -
GPS-Palm: 0.96
Deep-Palm: 0.63
182 - - -
GPS-Palm: 0.92
Deep-Palm: 0.78
206 SWISSPALM DBPTM CYSMODDB Scramblase
HeLa (29575903)
-
GPS-Palm: 0.85
Deep-Palm: 0.83
227 -
HeLa (29575903)
-
Deep-Palm: 0.43
230 -
HeLa (29575903)
-
Deep-Palm: 0.52
232 -
HeLa (29575903)
-
GPS-Palm: 0.69
Deep-Palm: 0.23
233 -
HeLa (29575903)
-
Deep-Palm: 0.18
247 -
HeLa (29575903)
Unknown (32651440)
cerebral cortex (36430497)
GPS-Palm: 0.67
Deep-Palm: 0.93
290 - - -
Deep-Palm: 0.53
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
1
HeLa cell
Specificity: 0.100
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.400
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
21 Y → C 0.002288 SNP Missense Mutation STAD
55 G → C 0.001764 SNP Missense Mutation LUAD
134 S → delinsILNC 0.001887 INS In Frame Ins UCEC
169 G → C 0.002033 SNP Missense Mutation LUSC
181 C → Y 0.002545 SNP Missense Mutation GBM
188 C → C 0.002294 SNP Silent OV
210 W → C 0.002033 SNP Missense Mutation LUSC
213 C → Y 0.001764 SNP Missense Mutation LUAD
254 C → Y 0.002506 SNP Missense Mutation COAD