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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
C9J7K9 PLSCR1; hCG_17108 Phospholipid scramblase Homo sapiens (Human) 311 aa

Protein Details: C9J7K9 (PLSCR1)

Protein Information
Accession C9J7K9
Protein Names Phospholipid scramblase
Gene Symbol PLSCR1; hCG_17108
Organism Homo sapiens (Human)
Length 311 aa
Isoforms No isoforms
Related PMIDs 29575903 32651440 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
PC3 cells
Specificity: 0.400
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.400
4/4 (100.0%)
1
Jurkat T cells
Specificity: 0.100
1/25 (4.0%)
1
HeLa cells
Specificity: 0.100
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNASHPETNL11PVGYPPQYPP21TAFQGPPGYS31GYPGPQVSYP41PPPAGHSGPG
51-10051PAGFPVPNQP61VYNQPVYNQP71VGAAGVPWMP81APQPPLNCPP91GLEYLSQIDQ
101-150101ILIHQQIELL111EVLTGFETNN121KYEIKNSFGQ131RVYFAAEDTD141CCTRNCCGPS
151-200151RPFTLRIIDN161MGQEVITLER171PLRCSSCCCP181CCLQEIEIQA191PPGVPIGYVI
201-250201QTWHPCLPKF211TIQNEKREDV221LKISGPCVVC231SCCGDVDFEI241KSLDEQCVVG
251-300251KISKHWTGIL261REAFTDADNF271GIQFPLDLDV281KMKAVMIGAC291FLIDFMFFES
301-311301TGSQEQKSGV311W
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
141 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) Scramblase 29575903
142 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) Scramblase 29575903
146 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) Scramblase 29575903
147 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) Scramblase 29575903
174 Prediction (High) - -
177 Prediction (High) - -
178 Prediction (High) - -
179 Prediction (High) - -
181 Prediction (High) - -
182 Prediction (High) - -
206 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) Scramblase 29575903
227 Experimental Scramblase 29575903
230 Experimental Scramblase 29575903
232 Experimental Prediction (Low) Scramblase 29575903
233 Experimental Scramblase 29575903
247 Experimental Prediction (Low) Scramblase 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
21 Y → C 0.002288 SNP Missense Mutation STAD
55 G → C 0.001764 SNP Missense Mutation LUAD
134 S → delinsILNC 0.001887 INS In Frame Ins UCEC
169 G → C 0.002033 SNP Missense Mutation LUSC
181 C → Y 0.002545 SNP Missense Mutation GBM
188 C → C 0.002294 SNP Silent OV
210 W → C 0.002033 SNP Missense Mutation LUSC
213 C → Y 0.001764 SNP Missense Mutation LUAD
254 C → Y 0.002506 SNP Missense Mutation COAD