Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| C9J8Q5 | ALDH5A1 | Succinate-semialdehyde dehydrogenase (EC 1.2.1.24) | Homo sapiens (Human) | 507 aa |
Protein Details: C9J8Q5 (ALDH5A1)
Protein Information
| Accession | C9J8Q5 |
|---|---|
| Protein Names | Succinate-semialdehyde dehydrogenase (EC 1.2.1.24) |
| Gene Symbol | ALDH5A1 |
| Organism | Homo sapiens (Human) |
| Length | 507 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.900
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.900
36/46 (78.3%)
2
DU145 cells
Specificity: 0.050
2/2 (100.0%)
2
PC3 cells
Specificity: 0.050
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MATCIWLRSC11GARRLGSTFP21GCRLRPRAGG31LVPASGPAPG41PAQLRCYAGR
51-10051LAGLSAALLR61TDSFVGGRWL71PAAATFPVQD81PASGAALGMV91ADCGVREARA
101-150101AVRAAYEAFC111RWREVSAKGK121PLKEAHGEIL131YSAFFLEWFS141EEARRVYGDI
151-200151IHTPAKDRRA161LVLKQPIGVA171AVITPWNFPS181AMITRKVGAA191LAAGCTVVVK
201-250201PAEDTPFSAL211ALAELASQAG221IPSGVYNVIP231CSRKNAKEVG241EAICTDPLVS
251-300251KISFTGSTTT261GKILLHHAAN271SVKRVSMELG281GLAPFIVFDS291ANVDQAVAGA
301-350301MASKFRNTGQ311TCVCSNQFLV321QRGIHDAFVK331AFAEAMKKNL341RVGNGFEEGT
351-400351TQGPLINEKA361VEKVEKQVND371AVSKGATVVT381GGKRHQLGKN391FFEPTLLCNV
401-450401TQDMLCTHEE411TFGPLAPVIK421FDTEEEAIAI431ANAADVGLAG441YFYSQDPAQI
451-500451WRVAEQLEVG461MVGVNEGLIS471SVECPFGGVK481QSGLGREGSK491YGIDEYLELK
501-507501YVCYGGL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 4 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 10 | Prediction (High) | - | - |
| 22 | Prediction (High) | - | - |
| 46 | Prediction (Low) | - | - |
| 93 | Prediction (High) | - | - |
| 110 | Prediction (High) | - | - |
| 195 | Prediction (High) | - | - |
| 231 | Prediction (High) | - | - |
| 244 | Prediction (High) | - | - |
| 314 | Prediction (Medium) | - | - |
| 474 | Prediction (Medium) | - | - |
| 503 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 340 | C → Ifs*9 | 0.027027 | DEL | Frame Shift Del | DLBC |