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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
C9J8Z4 IGSF8 Immunoglobulin superfamily member 8 Homo sapiens (Human) 301 aa

Protein Details: C9J8Z4 (IGSF8)

Protein Information
Accession C9J8Z4
Protein Names Immunoglobulin superfamily member 8
Gene Symbol IGSF8
Organism Homo sapiens (Human)
Length 301 aa
Isoforms No isoforms
Related PMIDs 19801377 26876311 31251020 32651440 32944167 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.760
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
38
LNCaP cells
Specificity: 0.760
38/46 (82.6%)
4
PC3 cells
Specificity: 0.080
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.080
4/4 (100.0%)
2
DU145 cells
Specificity: 0.040
2/2 (100.0%)
1
Jurkat T cells
Specificity: 0.020
1/25 (4.0%)
1
Prefrontal cortex
Specificity: 0.020
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGALRPTLLP11PSLPLLLLLM21LGMGCWAREV31LVPEGPLYRV41AGTAVSISCN
51-10051VTGYEGPAQQ61NFEWFLYRPE71APDTALGIVS81TKDTQFSYAV91FKSRVVAGEV
101-150101QVQRLQGDAV111VLKIARLQAQ121DAGIYECHTP131STDTRYLGSY141SGKVELRVLP
151-200151DVLQVSAAPP161GPRGRQAPTS171PPRMTVHEGQ181ELALGCLART191STQKHTHLAV
201-250201SFGRSVPEAP211VGRSTLQEVV221GIRSDLAVEA231GAPYAERLAA241GELRLGKEGT
251-300251DRYRMVVGGA261QAGDAGTYHC271TAAEWIQDPD281GSWAQIAEKR291AVLAHVDVQT
301-301301L
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
25 Prediction (Medium) - -
186 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
127 C → F 0.002033 SNP Missense Mutation LUSC
165 R → C 0.002141 SNP Missense Mutation SKCM
173 R → C 0.001887 SNP Missense Mutation UCEC
234 Y → C 0.002506 SNP Missense Mutation COAD
244 R → C 0.002506 SNP Missense Mutation COAD
246 G → C 0.001887 SNP Missense Mutation UCEC
337 R → C 0.001887 SNP Missense Mutation UCEC
420 R → C 0.001764 SNP Missense Mutation LUAD