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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
C9J9B4 ADAM10 ADAM metallopeptidase domain 10 Homo sapiens (Human) 125 aa

Protein Details: C9J9B4 (ADAM10)

Protein Information
Accession C9J9B4
Protein Names ADAM metallopeptidase domain 10
Gene Symbol ADAM10
Organism Homo sapiens (Human)
Length 125 aa
Isoforms No isoforms
Related PMIDs 19801377 31251020
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.947
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.947
36/46 (78.3%)
2
DU145 cells
Specificity: 0.053
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MVLLRVLILL11LSWAAGMGGQ21YGNPLNKYIR31HYEGLSYNVD41SLHQKHQRAK
51-10051RAVSHEDQFL61RLDFHAHGRH71FNLRMKRDTS81LFSDEFKVET91SNKVLDYDTS
101-125101HIYTGHIYDY111PHKYGPQGGC121ADHSV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
120 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
108 Y → C 0.002427 SNP Missense Mutation BLCA
389 F → C 0.002506 SNP Missense Mutation COAD
536 C → G 0.002545 SNP Missense Mutation GBM
594 C → W 0.001887 SNP Missense Mutation UCEC
607 C → F 0.002747 SNP Missense Mutation LIHC
639 C → Y 0.001764 SNP Missense Mutation LUAD
734 R → C 0.001887 SNP Missense Mutation UCEC
344* C → ? 0.002294 DEL Frame Shift Del OV