Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| C9JDE9 | ACAA1 | Acetyl-CoA acyltransferase 1 | Homo sapiens (Human) | 383 aa |
Protein Details: C9JDE9 (ACAA1)
Protein Information
| Accession | C9JDE9 |
|---|---|
| Protein Names | Acetyl-CoA acyltransferase 1 |
| Gene Symbol | ACAA1 |
| Organism | Homo sapiens (Human) |
| Length | 383 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32651440 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.902
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
37
LNCaP cells
Specificity: 0.902
37/46 (80.4%)
3
PC3 cells
Specificity: 0.073
3/4 (75.0%)
1
Jurkat T cells
Specificity: 0.024
1/25 (4.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MQRLQVVLGH11LRGPADSGWM21PQAAPCLSGA31PQASAADVVV41VHGRRTAICR
51-10051AGRGGFKDTT61PDELLSAVMT71AVLKDVNLRP81EQLGDICVGN91VLQPGAGAIM
101-150101ARIAQFLRVE111SMSLADRGNP121GNITSRLMEK131EKARDCLIPM141GITSENVAER
151-200151FGISREKQDT161FALASQQKAA171RAQSKGCFQA181EIVPVTTTVH191DDKGTKRSIT
201-250201VTQDEGIRPS211TTMEGLAKLK221PAFKKDGSTT231AGNSSQVSDG241AAAILLARRS
251-300251KAEELGLPIL261GVLRSYAVVG271VPPDIMGIGP281AYAIPVALQK291AGLTVSDVDI
301-350301FEINEAFASQ311AAYCVEKLRL321PPEKVNPLGG331AVALGHPLGC341TGARQVITLL
351-383351NELKRRGKRA361YGVVSMCIGT371GMGAAAVFEY381PGN
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 26 | Prediction (Low) | - | - |
| 49 | Prediction (Medium) | - | - |
| 136 | Prediction (Medium) | - | - |
| 177 | Prediction (Medium) | - | - |
| 314 | Prediction (Low) | - | - |
| 340 | Prediction (High) | - | - |
| 367 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 123 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 396 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |