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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
C9JE06 PLSCR1 Phospholipid scramblase Homo sapiens (Human) 249 aa

Protein Details: C9JE06 (PLSCR1)

Protein Information
Accession C9JE06
Protein Names Phospholipid scramblase
Gene Symbol PLSCR1
Organism Homo sapiens (Human)
Length 249 aa
Isoforms No isoforms
Related PMIDs 29575903 32651440 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
PC3 cells
Specificity: 0.667
4/4 (100.0%)
1
Jurkat T cells
Specificity: 0.167
1/25 (4.0%)
1
HeLa cells
Specificity: 0.167
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDKQNSQMNA11SHPETNLPVG21YPPQYPPTAF31QGPPGYSGYP41GPQVSYPPPP
51-10051AGHSGPGPAG61FPVPNQPVYN71QPVYNQPVGA81AGVPWMPAPQ91PPLNCPPGLE
101-150101YLSQIDQILI111HQQIELLEVL121TGFETNNKYE131IKNSFGQRVY141FAAEDTDCCT
151-200151RNCCGPSRPF161TLRIIDNMGQ171EVITLERPLR181CSSCCCPCCL191QEIEIQAPPG
201-249201VPIGYVIQTW211HPCLPKFTIQ221NEKREDVLKI231SGPCVVCSCC241GDVDFEIKS
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
148 CYSMODDB SWISSPALM DBPTM Prediction (High) Scramblase -
149 CYSMODDB SWISSPALM DBPTM Prediction (High) Scramblase -
153 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Scramblase -
154 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Scramblase -
181 Prediction (High) - -
184 Prediction (High) - -
185 Prediction (High) - -
186 Prediction (High) - -
188 Prediction (High) - -
189 Prediction (High) - -
213 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Scramblase -
234 Experimental Scramblase 29575903
237 Experimental Scramblase 29575903
239 Experimental Prediction (Low) Scramblase 29575903
240 Experimental Scramblase 29575903
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
21 Y → C 0.002288 SNP Missense Mutation STAD
55 G → C 0.001764 SNP Missense Mutation LUAD
134 S → delinsILNC 0.001887 INS In Frame Ins UCEC
169 G → C 0.002033 SNP Missense Mutation LUSC
181 C → Y 0.002545 SNP Missense Mutation GBM
188 C → C 0.002294 SNP Silent OV
210 W → C 0.002033 SNP Missense Mutation LUSC
213 C → Y 0.001764 SNP Missense Mutation LUAD
254 C → Y 0.002506 SNP Missense Mutation COAD