Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| C9JKI3 | CAV1 | Caveolin | Homo sapiens (Human) | 138 aa |
Protein Details: C9JKI3 (CAV1)
Protein Information
| Accession | C9JKI3 |
|---|---|
| Protein Names | Caveolin |
| Gene Symbol | CAV1 |
| Organism | Homo sapiens (Human) |
| Length | 138 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 32944167 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MADELSEKQV11YDAHTKEIDL21VNRDPKHLND31DVVKIDFEDV41IAEPEGTHSF
51-10051DGIWKASFTT61FTVTKYWFYR71LLSALFGIPM81ALIWGIYFAI91LSFLHIWAVV
101-138101PCIKSFLIEI111QCISRVYSIY121VHTVCDPLFE131AVGKIFSN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 102 | SWISSPALM DBPTM CYSMODDB | Caveolin |
HeLa
(29575903)
| - |
GPS-Palm: 0.79
Deep-Palm: 0.41
|
| 112 | SWISSPALM DBPTM CYSMODDB | Caveolin |
HeLa
(29575903)
| - |
GPS-Palm: 0.87
Deep-Palm: 0.16
|
| 125 | SWISSPALM DBPTM CYSMODDB | Caveolin |
HeLa
(29575903)
| - |
GPS-Palm: 0.69
Deep-Palm: 0.37
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
PC3
Specificity: 0.444
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.444
4/4 (100.0%)
1
DU145 cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 146 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 171 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 171 | R → C | 0.005435 | SNP | Missense Mutation | ESCA |