Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| C9JL26 | AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | Homo sapiens (Human) | 255 aa |
Protein Details: C9JL26 (AGPAT3)
Protein Information
| Accession | C9JL26 |
|---|---|
| Protein Names | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| Gene Symbol | AGPAT3 |
| Organism | Homo sapiens (Human) |
| Length | 255 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGLLAFLKTQ11FVLHLLVGFV21FVVSGLVINF31VQLCTLALWP41VSKQLYRRLN
51-10051CRLAYSLWSQ61LVMLLEWWSC71TECTLFTDQA81TVERFGKEHA91VIILNHNFEI
101-150101DFLCGWTMCE111RFGVLGSSKV121LAKKELLYVP131LIGWTWYFLE141IVFCKRKWEE
151-200151DRDTVVEGLR161RLSDYPEYMW171FLLYCEGTRF181TETKHRVSME191VAAAKGLPVL
201-250201KYHLLPRTKG211FTTAVKCLRG221TVAAVYDVTL231NFRGNKNPSL241LGILYGKKYE
251-255251ADMCV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 34 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.92
|
|
| 51 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.94
|
|
| 70 | - | - | - |
Deep-Palm: 0.18
|
|
| 73 | - | - | - |
Deep-Palm: 0.27
|
|
| 104 | - | - | - |
Deep-Palm: 0.56
|
|
| 109 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.80
|
|
| 144 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.72
|
|
| 175 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.48
|
|
| 217 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.97
|
|
| 254 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
2
LNCaP
Specificity: 0.500
2/2 (100.0%)
2
PC3
Specificity: 0.500
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 254 | C → C | 0.002294 | SNP | Silent | OV |
| 306 | W → C | 0.002545 | SNP | Missense Mutation | GBM |
| 314 | W → C | 0.002506 | SNP | Missense Mutation | COAD |
| 353 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 353 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 353 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 353 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 353 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |