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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
C9JPV8 AP2M1 AP-2 complex subunit mu Homo sapiens (Human) 458 aa

Protein Details: C9JPV8 (AP2M1)

Protein Information
Accession C9JPV8
Protein Names AP-2 complex subunit mu
Gene Symbol AP2M1
Organism Homo sapiens (Human)
Length 458 aa
Isoforms No isoforms
Related PMIDs 26876311 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.875
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.875
35/46 (76.1%)
4
PC3 cells
Specificity: 0.100
4/4 (100.0%)
1
Prefrontal cortex
Specificity: 0.025
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MIGGLFIYNH11KGEVLISRVY21RDDIGSRQAA31DSAVFSSSGP41FPGEWLEARN
51-10051AVDAFRVNVI61HARQQVRSPV71TNIARTSFFH81VKRSNIWLAA91VTKQNVNAAM
101-150101VFEFLYKMCD111VMAAYFGKIS121EENIKNNFVL131IYELLDEILD141FGYPQNSETG
151-200151ALKTFITQQG161IKSQHQTKEE171QSQITSQVTG181QIGWRREGIK191YRRNELFLDV
201-250201LESVNLLMSP211QGQVLSAHVS221GRVVMKSYLS231GMPECKFGMN241DKIVIEKQGK
251-300251GTADETSKSG261KQSIAIDDCT271FHQCVRLSKF281DSERSISFIP291PDGEFELMRY
301-350301RTTKDIILPF311RVIPLVREVG321RTKLEVKVVI331KSNFKPSLLA341QKIEVRIPTP
351-400351LNTSGVQVIC361MKGKAKYKAS371ENAIVWKIKR381MAGMKESQIS391AEIELLPTND
401-450401KKKWARPPIS411MNFEVPFAPS421GLKVRYLKVF431EPKLNYSDHD441VIKWVRYIGR
451-458451SGIYETRC
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
360 Prediction (High) - -
458 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
44 R → C 0.002033 SNP Missense Mutation LUSC
44 R → C 0.001887 SNP Missense Mutation UCEC
83 Y → C 0.001764 SNP Missense Mutation LUAD
246 C → Y 0.002747 SNP Missense Mutation LIHC
251 C → C 0.002033 SNP Silent LUSC
278 R → C 0.003774 SNP Missense Mutation UCEC
298 R → C 0.002506 SNP Missense Mutation COAD
397 S → C 0.002427 SNP Missense Mutation BLCA
423 R → C 0.001887 SNP Missense Mutation UCEC