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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
C9JZ87 TMEM106B Transmembrane protein 106B Homo sapiens (Human) 110 aa

Protein Details: C9JZ87 (TMEM106B)

Protein Information
Accession C9JZ87
Protein Names Transmembrane protein 106B
Gene Symbol TMEM106B
Organism Homo sapiens (Human)
Length 110 aa
Isoforms No isoforms
Related PMIDs 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
21
LNCaP cells
Specificity: 1.000
21/46 (45.7%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGKSLSHLPL11HSSKEDAYDG21VTSENMRNGL31VNSEVHNEDG41RNGDVSQFPY
51-10051VEFTGRDSVT61CPTCQGTGRI71PRGQENQLVA81LIPYSDQRLR91PRRTKLYVMA
101-110101SVFVCLLLSG
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
64 Prediction (Medium) - -
105 CYSMODDB SWISSPALM DBPTM Prediction (High) Transmembrane protein 106 N-terminal region -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
132 Y → Cfs*4 0.002506 DEL Frame Shift Del COAD
140 R → C 0.002288 SNP Missense Mutation STAD
180 R → C 0.002747 SNP Missense Mutation LIHC
180 R → C 0.001887 SNP Missense Mutation UCEC