Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| C9JZR2 | CTNND1 | Catenin delta 1 | Homo sapiens (Human) | 938 aa |
Protein Details: C9JZR2 (CTNND1)
Protein Information
| Accession | C9JZR2 |
|---|---|
| Protein Names | Catenin delta 1 |
| Gene Symbol | CTNND1 |
| Organism | Homo sapiens (Human) |
| Length | 938 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDDSEVESTA11SILASVKEQE21AQFEKLTRAL31EEERRHVSAQ41LERVRVSPQD
51-10051ANPLMANGTL61TRRHQNGRFV71GDADLERQKF81SDLKLNGPQD91HSHLLYSTIP
101-150101RMQEPGQIVE111TYTEEDPEGA121MSVVSVETSD131DGTTRRTETT141VKKVVKTVTT
151-200151RTVQPVAMGP161DGLPVDASSV171SNNYIQTLGR181DFRKNGNGGP191GPYVGQAGTA
201-250201TLPRNFHYPP211DGYSRHYEDG221YPGGSDNYGS231LSRVTRIEER241YRPSMEGYRA
251-300251PSRQDVYGPQ261PQVRVGGSSV271DLHRFHPEPY281GLEDDQRSMG291YDDLDYGMMS
301-350301DYGTARRTGT311PSDPRRRLRS321YEDMIGEEVP331SDQYYWAPLA341QHERGSLASL
351-400351DSLRKGGPPP361PNWRQPELPE371VIAMLGFRLD381AVKSNAAAYL391QHLCYRNDKV
401-450401KTDVRKLKGI411PVLVGLLDHP421KKEVHLGACG431ALKNISFGRD441QDNKIAIKNC
451-500451DGVPALVRLL461RKARDMDLTE471VITGTLWNLS481SHDSIKMEIV491DHALHALTDE
501-550501VIIPHSGWER511EPNEDCKPRH521IEWESVLTNT531AGCLRNVSSE541RSEARRKLRE
551-600551CDGLVDALIF561IVQAEIGQKD571SDSKLVENCV581CLLRNLSYQV591HREIPQAERY
601-650601QEAAPNVANN611TGPHAASCFG621AKKGKDEWFS631RGKKPIEDPA641NDTVDFPKRT
651-700651SPARGYELLF661QPEVVRIYIS671LLKESKTPAI681LEASAGAIQN691LCAGRWTYGR
701-750701YIRSALRQEK711ALSAIADLLT721NEHERVVKAA731SGALRNLAVD741ARNKELIGKH
751-800751AIPNLVKNLP761GGQQNSSWNF771SEDTVISILN781TINEVIAENL791EAAKKLRETQ
801-850801GIEKLVLINK811SGNRSEKEVR821AAALVLQTIW831GYKELRKPLE841KEGWKKSDFQ
851-900851VNLNNASRSQ861SSHSYDDSTL871PLIDRNQKSD881KKPDREEIQM891SNMGSNTKSL
901-938901DNNYSTPNER911GDHNRTLDRS921GDLGDMEPLK931GTTPLMKI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 394 | SWISSPALM DBPTM CYSMODDB | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.84
Deep-Palm: 0.96
|
| 429 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.95
|
|
| 450 | - | - |
LNCaP
(31251020)
cerebral cortex
(36430497)
|
GPS-Palm: 0.81
Deep-Palm: 0.98
|
|
| 516 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.16
|
|
| 533 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.90
Deep-Palm: 0.94
|
|
| 551 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.88
Deep-Palm: 0.97
|
|
| 579 | - | - |
LNCaP
(31251020)
cerebral cortex
(36430497)
|
GPS-Palm: 0.94
Deep-Palm: 0.95
|
|
| 581 | - | - |
LNCaP
(31251020)
cerebral cortex
(36430497)
|
GPS-Palm: 0.92
Deep-Palm: 0.94
|
|
| 618 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.90
Deep-Palm: 0.83
|
| 692 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.88
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
4
PC3
Specificity: 0.250
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.250
4/4 (100.0%)
2
HeLa cell
Specificity: 0.125
2/2 (100.0%)
1
LNCaP
Specificity: 0.062
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
LNCaP cells (Mass)
Specificity: 0.188
3/4 (75.0%)
2
Cerebral Cortex (Mass)
Specificity: 0.125
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 280 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 290 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 450 | C → W | 0.001887 | SNP | Missense Mutation | UCEC |
| 497 | L → Cfs*13 | 0.002427 | DEL | Frame Shift Del | BLCA |
| 533 | C → C | 0.001887 | SNP | Silent | UCEC |
| 777 | S → C | 0.004219 | SNP | Missense Mutation | SARC |