Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| D6RD16 | CANX | Calnexin | Homo sapiens (Human) | 96 aa |
Protein Details: D6RD16 (CANX)
Protein Information
| Accession | D6RD16 |
|---|---|
| Protein Names | Calnexin |
| Gene Symbol | CANX |
| Organism | Homo sapiens (Human) |
| Length | 96 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 19801377 21076176 22496122 26876311 29575903 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEGKWLLCML11LVLGTAIVEA21HDGHDDDVID31IEDDLDDVIE41EVEDSKPDTT
51-9651APPSSPKVTY61KAPVPTGEVY71FADSFDRGTL81SGKVGGRGNE91GVKASR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | - | - | - |
Deep-Palm: 0.05
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.200
4
LNCaP
Specificity: 0.200
4/4 (100.0%)
4
PC3
Specificity: 0.200
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.200
4/4 (100.0%)
3
Jurkat T cell
Specificity: 0.150
3/3 (100.0%)
2
HeLa cell
Specificity: 0.100
2/2 (100.0%)
1
EC cell
Specificity: 0.050
1/1 (100.0%)
1
frontal cortex
Specificity: 0.050
1/1 (100.0%)
1
DU145 cell
Specificity: 0.050
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 438 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 456 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 480 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |