Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| D6RDX7 | EMB | Embigin | Homo sapiens (Human) | 273 aa |
Protein Details: D6RDX7 (EMB)
Protein Information
| Accession | D6RDX7 |
|---|---|
| Protein Names | Embigin |
| Gene Symbol | EMB |
| Organism | Homo sapiens (Human) |
| Length | 273 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32651440 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRALPGLLEA11RARTPRLLLL21QCLLAAARPS31SADGSAPDSP41FTSPPLREEI
51-10051MANNFSLESH61NISLTGSTLY71TQYRFTIINS81KQMGSYSCFF91REEKEQRGTF
101-150101NFKVPELHGK111NKPLISYVGD121STVLTCKCQN131CFPLNWTWYS141SNGSVKVPVG
151-200151VQMNKYVING161TYANETKLKI171TQLLEEDGES181YWCRALFQLG191ESEEHIELVV
201-250201LSYLVPLKPF211LVIVAEVILL221VATILLCEKY231TQKKKKHSDE241GKEFEQIEQL
251-273251KSDDSNGIEN261NVPRHRKNES271LGQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 22 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.99
|
|
| 88 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.24
|
|
| 126 | - | - | - |
Deep-Palm: 0.06
|
|
| 128 | - | - | - |
Deep-Palm: 0.03
|
|
| 131 | - | - | - |
Deep-Palm: 0.02
|
|
| 183 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.87
|
|
| 227 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
LNCaP
Specificity: 0.333
2/2 (100.0%)
2
PC3
Specificity: 0.333
2/2 (100.0%)
1
Jurkat T cell
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.167
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 124 | Y → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 180 | C → Y | 0.002545 | SNP | Missense Mutation | GBM |
| 185 | C → W | 0.002288 | SNP | Missense Mutation | STAD |
| 192 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 238 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 324 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |