Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| D6RFE4 | ADH5 | Alcohol dehydrogenase class-3 | Homo sapiens (Human) | 115 aa |
Protein Details: D6RFE4 (ADH5)
Protein Information
| Accession | D6RFE4 |
|---|---|
| Protein Names | Alcohol dehydrogenase class-3 |
| Gene Symbol | ADH5 |
| Organism | Homo sapiens (Human) |
| Length | 115 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 1.000
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MANEVIKCKA11AVAWEAGKPL21SIEEIEVAPP31KAHEVRIKII41ATAVCHTDAY
51-10051TLSGADPEGC61FPVILGHEGA71GIVESVGEGV81TKLKAGDTVI91PLYIPQCGEC
101-115101KFCLNPKTNL111CQKIR
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 8 | Prediction (Medium) | - | - |
| 45 | Prediction (Low) | - | - |
| 97 | Experimental CYSMODDB SWISSPALM DBPTM | Alcohol dehydrogenase GroES-like domain | 29575903 |
| 100 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) | Alcohol dehydrogenase GroES-like domain | 29575903 |
| 103 | Experimental CYSMODDB SWISSPALM DBPTM | - | 29575903 |
| 111 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 174 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 174 | C → F | 0.002294 | SNP | Missense Mutation | OV |
| 312 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |