Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| D6RFE4 | ADH5 | Alcohol dehydrogenase class-3 | Homo sapiens (Human) | 115 aa |
Protein Details: D6RFE4 (ADH5)
Protein Information
| Accession | D6RFE4 |
|---|---|
| Protein Names | Alcohol dehydrogenase class-3 |
| Gene Symbol | ADH5 |
| Organism | Homo sapiens (Human) |
| Length | 115 aa |
| Isoforms | No isoforms |
| Related PMIDs | 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MANEVIKCKA11AVAWEAGKPL21SIEEIEVAPP31KAHEVRIKII41ATAVCHTDAY
51-10051TLSGADPEGC61FPVILGHEGA71GIVESVGEGV81TKLKAGDTVI91PLYIPQCGEC
101-115101KFCLNPKTNL111CQKIR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | GroES-like superfamily | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.09
|
|
| 45 | Alcohol dehydrogenase-like, N-terminal ALCOHOL DEHYDROGENASE GroES-like superfamily | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.86
|
|
| 60 | - | - | - |
Deep-Palm: 0.80
|
|
| 97 | SWISSPALM DBPTM CYSMODDB | Alcohol dehydrogenase GroES-like domain | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.94
|
| 100 | SWISSPALM DBPTM CYSMODDB | Alcohol dehydrogenase GroES-like domain | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.71
Deep-Palm: 0.52
|
| 103 | SWISSPALM DBPTM CYSMODDB | - | - | - |
Deep-Palm: 0.12
|
| 111 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
cerebral cortex
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 174 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 174 | C → F | 0.002294 | SNP | Missense Mutation | OV |
| 312 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |