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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
D6RFH4 CYB5B Cytochrome b5 type B Homo sapiens (Human) 125 aa

Protein Details: D6RFH4 (CYB5B)

Protein Information
AccessionD6RFH4
Protein NamesCytochrome b5 type B
Gene SymbolCYB5B
OrganismHomo sapiens (Human)
Length125 aa
IsoformsNo isoforms
Related PMIDs 22496122 31251020 32651440 32944167 36430497
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGSMATAEA11SGSDGKGQEV21ETSVTYYRLE31EVAKRNSLKE41LWLVIHGRVY
51-10051DVTRFLNEHP61GGEEVLLEQA71GVDASESFED81VGHSSDAREM91LKQYYIGDIH
101-125101PSDLKPESGS111KDPSKNDTCK121RLVSP
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
119 - - -
GPS-Palm: 0.85
Deep-Palm: 0.03
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
3
PC3
Specificity: 0.333
3/3 (100.0%)
2
LNCaP
Specificity: 0.222
2/2 (100.0%)
2
cerebral cortex
Specificity: 0.222
2/2 (100.0%)
1
Jurkat T cell
Specificity: 0.111
1/1 (100.0%)
1
EC cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
46 Y → C 0.001764 SNP Missense Mutation LUAD