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UniProt ID Gene Symbol Protein Name Organism Length Action
D6RGF4 ABCE1 ATP binding cassette subfamily E … Homo sapiens (Human) 210 aa

Protein Details: D6RGF4 (ABCE1)

Protein Information
AccessionD6RGF4
Protein NamesATP binding cassette subfamily E member 1
Gene SymbolABCE1
OrganismHomo sapiens (Human)
Length210 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MADKLTRIAI11VNHDKCKPKK21CRQECKKSCP31VVRMGKLCIE41VTPQSKIAWI
51-10051SETLCIGCGI61CIKKCPFGAL71SIVNLPSNLE81KETTHRYCAN91AFKLHRLPIP
101-150101RPGEVLGLVG111TNGIGKSTAL121KILAGKQKPN131LGKYDDPPDW141QEILTYFRGS
151-200151ELQNYFTKIL161EDDLKAIIKP171QYVDQIPKAA181KGTVGSILDR191KDETKTQAIV
201-210201CQQLDLTHLK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
16 RLI1 RNase L inhibitor RLI-like, possible metal-binding domain - -
GPS-Palm: 0.69
Deep-Palm: 0.23
21 RLI1 RNase L inhibitor RLI-like, possible metal-binding domain - -
Deep-Palm: 0.46
25 RLI1 RNase L inhibitor RLI-like, possible metal-binding domain - -
GPS-Palm: 0.79
Deep-Palm: 0.55
29 RLI1 RNase L inhibitor RLI-like, possible metal-binding domain - -
GPS-Palm: 0.87
Deep-Palm: 0.74
38 4Fe-4S ferredoxins P-loop containing nucleoside triphosphate hydrolase 4Fe-4S ferredoxin-type, iron-sulphur binding domain RLI1 - -
GPS-Palm: 0.93
Deep-Palm: 0.89
55 - - -
GPS-Palm: 0.95
Deep-Palm: 0.90
58 - - -
GPS-Palm: 0.77
Deep-Palm: 0.91
61 - - -
GPS-Palm: 0.80
Deep-Palm: 0.90
65 SWISSPALM DBPTM CYSMODDB 4Fe-4S binding domain -
Unknown (32651440)
GPS-Palm: 0.85
Deep-Palm: 0.95
88 - - -
GPS-Palm: 0.77
Deep-Palm: 0.85
201 - - -
GPS-Palm: 0.72
Deep-Palm: 0.13
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
PC3
Specificity: 0.600
3/3 (100.0%)
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
88 C → Y 0.001887 SNP Missense Mutation UCEC
134 Y → C 0.002747 SNP Missense Mutation LIHC
225 F → C 0.001887 SNP Missense Mutation UCEC
287 C → C 0.001887 SNP Silent UCEC
290 Y → C 0.001014 SNP Missense Mutation BRCA
346 C → C 0.002506 SNP Silent COAD
425 R → C 0.002506 SNP Missense Mutation COAD
425 R → C 0.007299 SNP Missense Mutation READ
425 R → C 0.001887 SNP Missense Mutation UCEC
483 Y → C 0.015152 SNP Missense Mutation KICH
506 R → C 0.001887 SNP Missense Mutation UCEC
527 Y → C 0.015152 SNP Missense Mutation KICH