Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| D6RGF4 | ABCE1 | ATP binding cassette subfamily E … | Homo sapiens (Human) | 210 aa |
Protein Details: D6RGF4 (ABCE1)
Protein Information
| Accession | D6RGF4 |
|---|---|
| Protein Names | ATP binding cassette subfamily E member 1 |
| Gene Symbol | ABCE1 |
| Organism | Homo sapiens (Human) |
| Length | 210 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
23
LNCaP cells
Specificity: 1.000
23/46 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MADKLTRIAI11VNHDKCKPKK21CRQECKKSCP31VVRMGKLCIE41VTPQSKIAWI
51-10051SETLCIGCGI61CIKKCPFGAL71SIVNLPSNLE81KETTHRYCAN91AFKLHRLPIP
101-150101RPGEVLGLVG111TNGIGKSTAL121KILAGKQKPN131LGKYDDPPDW141QEILTYFRGS
151-200151ELQNYFTKIL161EDDLKAIIKP171QYVDQIPKAA181KGTVGSILDR191KDETKTQAIV
201-210201CQQLDLTHLK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 16 | Prediction (Low) | - | - |
| 25 | Prediction (Medium) | - | - |
| 29 | Prediction (Medium) | - | - |
| 38 | Prediction (High) | - | - |
| 55 | Prediction (High) | - | - |
| 58 | Prediction (Low) | - | - |
| 61 | Prediction (Medium) | - | - |
| 65 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | 4Fe-4S binding domain | - |
| 88 | Prediction (Low) | - | - |
| 201 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 88 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 134 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 225 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 287 | C → C | 0.001887 | SNP | Silent | UCEC |
| 290 | Y → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 346 | C → C | 0.002506 | SNP | Silent | COAD |
| 425 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 425 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 425 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 483 | Y → C | 0.015152 | SNP | Missense Mutation | KICH |
| 506 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 527 | Y → C | 0.015152 | SNP | Missense Mutation | KICH |