Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| D6RGY2 | CANX | Calnexin | Homo sapiens (Human) | 528 aa |
Protein Details: D6RGY2 (CANX)
Protein Information
| Accession | D6RGY2 |
|---|---|
| Protein Names | Calnexin |
| Gene Symbol | CANX |
| Organism | Homo sapiens (Human) |
| Length | 528 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 21076176 22496122 26876311 29575903 31251020 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
45
LNCaP cells
Specificity: 0.750
45/46 (97.8%)
6
Jurkat T cells
Specificity: 0.100
6/25 (24.0%)
4
PC3 cells
Specificity: 0.067
4/4 (100.0%)
2
DU145 cells
Specificity: 0.033
2/2 (100.0%)
1
HeLa cells
Specificity: 0.017
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.017
1/2 (50.0%)
1
Prefrontal cortex
Specificity: 0.017
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEGKWLLCML11LVLGTAIVEA21HDGHDDDVID31IEDDLDDVIE41EVEEMKESKL
51-10051PGDKGLVLMS61RAKHHAISAK71LNKPFLFDTK81PLIVQYEVNF91QNGIECGGAY
101-150101VKLLSKTPEL111NLDQFHDKTP121YTIMFGPDKC131GEDYKLHFIF141RHKNPKTGIY
151-200151EEKHAKRPDA161DLKTYFTDKK171THLYTLILNP181DNSFEILVDQ191SVVNSGNLLN
201-250201DMTPPVNPSR211EIEDPEDRKP221EDWDERPKIP231DPEAVKPDDW241DEDAPAKIPD
251-300251EEATKPEGWL261DDEPEYVPDP271DAEKPEDWDE281DMDGEWEAPQ291IANPRCESAP
301-350301GCGVWQRPVI311DNPNYKGKWK321PPMIDNPSYQ331GIWKPRKIPN341PDFFEDLEPF
351-400351RMTPFSAIGL361ELWSMTSDIF371FDNFIICADR381RIVDDWANDG391WGLKKAADGA
401-450401AEPGVVGQMI411EAAEERPWLW421VVYILTVALP431VFLVILFCCS441GKKQTSGMEY
451-500451KKTDAPQPDV461KEEEEEKEEE471KDKGDEEEEG481EEKLEEKQKS491DAEEDGGTVS
501-528501QEEEDRKPKA511EEDEILNRSP521RNRKPRRE
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 96 | Prediction (Low) | - | - |
| 302 | Prediction (Medium) | - | - |
| 377 | Prediction (Medium) | - | - |
| 438 | Prediction (High) | - | - |
| 439 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 438 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 456 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 480 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |