Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
D6RJ96 HSPA4L Heat shock protein family A … Homo sapiens (Human) 531 aa

Protein Details: D6RJ96 (HSPA4L)

Protein Information
Accession D6RJ96
Protein Names Heat shock protein family A (Hsp70) member 4 like
Gene Symbol HSPA4L
Organism Homo sapiens (Human)
Length 531 aa
Isoforms No isoforms
Related PMIDs 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
19
LNCaP cells
Specificity: 1.000
19/46 (41.3%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSVVGIDLGF11LNCYIAVARS21GGIETIANEY31SDRCTPACIS41LGSRTRAIGN
51-10051AAKSQIVTNV61RNTIHGFKKL71HGRSFDDPIV81QTERIRLPYE91LQKMPNGSAG
101-150101VKIPSFFTDA111ERRSVMAAAQ121VAGLNCLRLM131NETTAVALAY141GIYKQDLPPL
151-200151DEKPRNVVFI161DMGHSAYQVL171VCAFNKGKLK181VLATTFDPYL191GGRNFDEALV
201-250201DYFCDEFKTK211YKINVKENSR221ALLRLYQECE231KLKKLMSANA241SDLPLNIECF
251-300251MNDLDVSSKM261NRAQFEQLCA271SLLARVEPPL281KAVMEQANLQ291REDISSIEIV
301-350301GGATRIPAVK311EQITKFFLKD321ISTTLNADEA331VARGCALQCA341ILSPAFKVRE
351-400351FSITDLVPYS361ITLRWKTSFE371DGSGECEVFC381KNHPAPFSKV391ITFHKKEPFE
401-450401LEAFYTNLHE411VPYPDARIGS421FTIQNVFPQS431DGDSSKVKVK441VRVNIHGIFS
451-500451VASASVIEKQ461NLEGDHSDAP471METETSFKNE481NKDNMDKMQV491DQEEGHQKCH
501-531501AEHTPEEEID511HTGAKTKSAV521SDKQDRLNQT531L
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
13 Prediction (Low) - -
34 Prediction (Low) - -
38 Prediction (Low) - -
126 Prediction (High) - -
172 Prediction (Medium) - -
204 Prediction (Medium) - -
229 Prediction (Medium) - -
269 Prediction (High) - -
335 CYSMODDB SWISSPALM DBPTM Prediction (Low) Hsp70 protein -
339 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Hsp70 protein -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
14 Y → C 0.007299 SNP Missense Mutation READ
428 F → C 0.001887 SNP Missense Mutation UCEC
483 R → C 0.001014 SNP Missense Mutation BRCA
483 R → C 0.002506 SNP Missense Mutation COAD
483 R → C 0.004283 SNP Missense Mutation SKCM
483 R → C 0.011321 SNP Missense Mutation UCEC
518 F → C 0.002033 SNP Missense Mutation LUSC
740 C → R 0.002427 SNP Missense Mutation BLCA