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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E5RFT1 SLC39A14 Metal cation symporter ZIP14 (Solute … Homo sapiens (Human) 201 aa

Protein Details: E5RFT1 (SLC39A14)

Protein Information
Accession E5RFT1
Protein Names Metal cation symporter ZIP14 (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14)
Gene Symbol SLC39A14
Organism Homo sapiens (Human)
Length 201 aa
Isoforms No isoforms
Related PMIDs 19801377 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.828
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.828
24/46 (52.2%)
3
PC3 cells
Specificity: 0.103
3/4 (75.0%)
2
DU145 cells
Specificity: 0.069
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKKTFYKRLL11LYFIALAIGT21LYSNALFQLI31PEAFGFNPLE41DYYVSKSAVV
51-10051FGGFYLFFFT61EKILKILLKQ71KNEHHHGHSH81YASESLPSKK91DQEEGVMEKL
101-150101QNGDLDHMIP111QHCSSELDGK121APMVDEKVIV131GSLSVQDLQA141SQSACYWLKG
151-200151VRYSDIGTLA161WMITLSDGLH171NFIDGLAIGA181SFTVSVFQGI191STSVAILCEE
201-201201F
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
145 CYSMODDB SWISSPALM DBPTM Prediction (Medium) - -
198 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
224 S → C 0.002033 SNP Missense Mutation LUSC
322 C → Y 0.002288 SNP Missense Mutation STAD
329 R → C 0.002506 SNP Missense Mutation COAD
366 G → C 0.002506 SNP Missense Mutation COAD
420 G → C 0.001764 SNP Missense Mutation LUAD