Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E5RFT1 | SLC39A14 | Metal cation symporter ZIP14 (Solute … | Homo sapiens (Human) | 201 aa |
Protein Details: E5RFT1 (SLC39A14)
Protein Information
| Accession | E5RFT1 |
|---|---|
| Protein Names | Metal cation symporter ZIP14 (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) |
| Gene Symbol | SLC39A14 |
| Organism | Homo sapiens (Human) |
| Length | 201 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKKTFYKRLL11LYFIALAIGT21LYSNALFQLI31PEAFGFNPLE41DYYVSKSAVV
51-10051FGGFYLFFFT61EKILKILLKQ71KNEHHHGHSH81YASESLPSKK91DQEEGVMEKL
101-150101QNGDLDHMIP111QHCSSELDGK121APMVDEKVIV131GSLSVQDLQA141SQSACYWLKG
151-200151VRYSDIGTLA161WMITLSDGLH171NFIDGLAIGA181SFTVSVFQGI191STSVAILCEE
201-201201F
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 113 | - | - | - |
Deep-Palm: 0.45
|
|
| 145 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.95
|
| 198 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 224 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 322 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 329 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 366 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 420 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |